X0508 4 2025-06-09 false 0001082554 UNITED THERAPEUTICS Corp UTHR 0001636178 EDGEMOND JAMES C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 false true false false CFO AND TREASURER true Common Stock 2025-06-09 4 M false 12000.00 117.76 A 20118.00 D Common Stock 2025-06-09 4 S false 3595.00 325.4396 D 16523.00 D Common Stock 2025-06-09 4 S false 305.00 326.5646 D 16218.00 D Common Stock 2025-06-09 4 S false 100.00 328.28 D 16118.00 D Common Stock 2025-06-09 4 S false 7700.00 325.2037 D 8418.00 D Common Stock 2025-06-09 4 S false 300.00 326.8067 D 8118.00 D Stock Option 117.76 2025-06-09 4 M false 12000.00 0.00 D 2021-03-15 2027-03-15 Common Stock 12000.00 87500.00 D This is an exercise of stock options and sale of the resulting shares pursuant to a pre-arranged 10b5-1 plan entered into by the reporting person on November 6, 2024. This transaction was executed in multiple trades at prices ranging from $325.00 to $325.87. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $326.04 to $326.58. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $325.00 to $325.95. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $326.57 to $327.28. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2025-06-10