X0508 4 2026-03-05 false 0001082554 UNITED THERAPEUTICS Corp UTHR 0001231589 MAHON PAUL A C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 false true false false EVP & GENERAL COUNSEL true Common Stock 2026-03-05 4 M false 8300.00 146.03 A 45144.00 D Common Stock 2026-03-05 4 S false 368.00 479.4271 D 44776.00 D Common Stock 2026-03-05 4 S false 1602.00 480.2186 D 43174.00 D Common Stock 2026-03-05 4 S false 720.00 481.3322 D 42454.00 D Common Stock 2026-03-05 4 S false 1177.00 482.6801 D 41277.00 D Common Stock 2026-03-05 4 S false 1086.00 483.5391 D 40191.00 D Common Stock 2026-03-05 4 S false 1398.00 484.5512 D 38793.00 D Common Stock 2026-03-05 4 S false 1006.00 485.3236 D 37787.00 D Common Stock 2026-03-05 4 S false 743.00 486.517 D 37044.00 D Common Stock 2026-03-05 4 S false 200.00 487.652 D 36844.00 D Stock Option 146.03 2026-03-05 4 M false 8300.00 0.00 D 2020-03-15 2027-03-15 Common Stock 8300.00 33500.00 D This is an exercise of stock options and sale of the resulting shares pursuant to a pre-arranged 10b5-1 plan entered into by the reporting person on August 11, 2025. This transaction was executed in multiple trades at prices ranging from $486.41 to $486.72. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $487.475 to $487.77. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Includes 63 shares of common stock acquired on March 4, 2026 under the United Therapeutics Employee Stock Purchase Plan. This transaction was executed in multiple trades at prices ranging from $478.82 to $479.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $479.82 to $480.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $481.02 to $481.46. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $482.025 to $482.86. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $483.07 to $484.06. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $484.07 to $484.95. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $485.10 to $485.61. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2026-03-05