X0508 4 2025-10-16 false 0001082554 UNITED THERAPEUTICS Corp UTHR 0001231589 MAHON PAUL A C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 false true false false EVP & GENERAL COUNSEL true Common Stock 2025-10-16 4 M false 11000.00 135.42 A 47781.00 D Common Stock 2025-10-16 4 S false 1908.00 428.5087 D 45873.00 D Common Stock 2025-10-16 4 S false 1092.00 429.6114 D 44781.00 D Common Stock 2025-10-16 4 S false 955.00 430.5883 D 43826.00 D Common Stock 2025-10-16 4 S false 2516.00 431.7167 D 41310.00 D Common Stock 2025-10-16 4 S false 2078.00 432.5891 D 39232.00 D Common Stock 2025-10-16 4 S false 1652.00 433.4507 D 37580.00 D Common Stock 2025-10-16 4 S false 798.00 434.7578 D 36782.00 D Common Stock 2025-10-16 4 S false 1.00 435.42 D 36781.00 D Stock Option 135.42 2025-10-16 4 M false 11000.00 0.00 D 2023-03-15 2027-03-15 Common Stock 11000.00 33000.00 D This is an exercise of stock options and sale of the resulting shares pursuant to a pre-arranged 10b5-1 plan entered into by the reporting person on December 24, 2024. This transaction was executed in multiple trades at prices ranging from $428.15 to $429.13. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $429.15 to $430.14. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $430.16 to $431.15. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $431.16 to $432.14. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $432.165 to $433.15. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $433.17 to $433.89. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $434.30 to $435.24. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2025-10-20