X0306 4 2015-06-03 0001082554 UNITED THERAPEUTICS Corp UTHR 0001106578 ROTHBLATT MARTINE A C/O UNITED THERAPEUTICS CORPORATION 1040 SPRING STREET SILVER SPRING MD 20910 1 1 Chairman & Co-CEO Common Stock 2015-06-03 4 M 0 2211 63.22 A 2451 D Common Stock 2015-06-03 4 S 0 100 182.34 D 2351 D Common Stock 2015-06-03 4 S 0 911 183.8299 D 1440 D Common Stock 2015-06-03 4 S 0 800 184.7938 D 640 D Common Stock 2015-06-03 4 S 0 400 185.93 D 240 D Common Stock 166 I By Spouse Common Stock 625031.05 I By Trusts Stock Options 63.22 2015-06-03 4 M 0 2211 0 D 2010-12-31 2020-12-31 Common Stock 2211 413476 D This exercise of stock options and corresponding sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person. This transaction was executed in multiple trades at prices ranging from $183.35 to $184.13. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $184.38 to $185.25. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $185.85 to $186.00. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2015-06-03