X0609 4/A 2026-05-26 2026-05-27 false 0001082554 UNITED THERAPEUTICS Corp UTHR 0001106578 ROTHBLATT MARTINE A false C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 true true false false Chairperson & CEO true Common Stock 2026-05-26 4 S false 1500.00 575.9649 D 43153.00 D This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 17, 2027; or (b) December 31, 2026. The Form 4 being amended originally used transaction code P as a result of administrative error. This amendment is being filed to use the correct transaction code S. The transaction was at all times reported as a disposition of shares: the original Form 4 designated the shares as Disposed of "(D)" in Column 4, reported a corresponding reduction in the Amount of Securities Beneficially Owned Following the Reported Transaction (from 44,653 shares to 43,153 shares), and, as described in footnote 1, disclosed that the transaction was a sale of shares acquired on option exercise pursuant to the reporting person's Rule 10b5-1 trading plan. This transaction was executed in multiple trades at prices ranging from $575.51 to $576.50. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2026-06-02