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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Cash flows from operating activities:      
Net loss $ (25,406) $ (17,278) $ (28,569)
Adjustments to reconcile net loss to net cash from operating activities:      
Depreciation 18 26 28
Amortization of warrant issuance costs 0 0 30
Stock-based compensation 4,055 3,986 5,398
Changes in assets and liabilities:      
Prepaid expenses and other assets 258 382 451
Accounts payable 636 (1,392) (477)
Other liabilities 0 140 0
Accrued payroll and related expenses (1,856) 695 232
Accounts receivable (6) 0 0
Related-party payable 0 0 (11)
Income tax liability 3 (3) (4)
Deferred revenue 0 (1,500) 1,000
Net cash used in operating activities (22,298) (14,944) (21,922)
Cash flows from investing activities:      
Purchase of property and equipment 0 0 (13)
Purchase of investments (3,090) (946) (10,527)
Proceeds from sale or maturity of investments 2,720 8,741 11,240
Net cash (used in) provided by investing activities (370) 7,795 700
Cash flows from financing activities:      
Proceeds from exercise of options 135 22 20
Proceeds from sale of common stock 27,051 3,677 19,196
Payments of taxes on cashless exercise of restricted stock units (42) (42) (93)
Net cash provided by financing activities 27,144 3,657 19,123
Net increase (decrease) in cash and cash equivalents 4,476 (3,492) (2,099)
Cash and cash equivalents, beginning of period 3,135 6,627 8,726
Cash and cash equivalents, end of period 7,611 3,135 6,627
Cash paid for income taxes 3 5 126
ASU Topic 606 [Member]      
Cash flows from financing activities:      
Deferred revenue reclassified to retained earnings - ASC 606 adoption $ 2,500 $ 0 $ 0