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Quarterly Financial Information (unaudited) (Tables)
 12 Months Ended
Dec. 31, 2018
Quarterly Financial Information (unaudited) [Abstract]  
Quarterly Financial Information
  
First
  
Second
  
Third
  
Fourth
 
     
(in thousands except per share)
    
2018
            
Revenue
 
$
6
  
$
16
  
$
7
  
$
34
 
Loss from operations
 
$
(7,608
)
 
$
(6,462
)
 
$
(4,948
)
 
$
(6,439
)
Net loss
 
$
(7,605
)
 
$
(6,450
)
 
$
(4,934
)
 
$
(6,417
)
Basic and diluted (loss) per common share
 
$
(0.13
)
 
$
(0.10
)
 
$
(0.08
)
 
$
(0.09
)

  
First
  
Second
  
Third
  
Fourth
 
     
(in thousands except per share)
    
2017
            
Revenue
 
$
375
  
$
396
  
$
375
  
$
401
 
Loss from operations
 
$
(3,906
)
 
$
(3,811
)
 
$
(3,562
)
 
$
(6,042
)
Net loss
 
$
(3,894
)
 
$
(3,798
)
 
$
(3,552
)
 
$
(6,034
)
Basic and diluted (loss) per common share
 
$
(0.07
)
 
$
(0.07
)
 
$
(0.06
)
 
$
(0.10
)