CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015
Cash flows from operating activities:
Net loss	$ (21,335)	$ (21,498)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	22	19
Amortization of warrant issuance costs	30	61
Stock-based compensation	3,979	5,326
Change in value of derivative liability	0	117
Changes in assets and liabilities:
Prepaid expenses and other assets	238	182
Accounts payable and accrued liabilities	549	(2,176)
Accrued payroll and related expenses	(1,383)	0
Royalty payable	884	(5,071)
Related party payable	83	(81)
Income tax liability	0	(8)
Deferred revenue	1,375	1,375
Net cash used in operating activities	(15,558)	(21,754)
Cash flows from investing activities:
Purchase of property and equipment	(14)	(4)
Purchase of investments	(7,888)	(6,234)
Proceeds from sale or maturity of investments	8,615	18,009
Net cash provided by investing activities	713	11,771
Cash flows from financing activities:
Proceeds from exercise of options	20	165
Proceeds from exercise of warrants	0	431
Proceeds from sale of common stock	14,626	719
Net cash provided by financing activities	14,646	1,315
Net decrease in cash and cash equivalents	(199)	(8,668)
Cash and cash equivalents, beginning of period	8,726	18,658
Cash and cash equivalents, end of period	8,527	9,990
Cash paid for income taxes	126	6
Non-cash transactions
Fair value of warrants issued for services	$ 0	$ 121