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Strategic Agreements - Patent Purchase Agreement with Indivior - Additional Information (Detail) - USD ($) $ in Thousands		1 Months Ended	3 Months Ended		6 Months Ended		12 Months Ended
	Sep. 26, 2017	Sep. 30, 2017	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018	Dec. 31, 2018	Dec. 31, 2017	Jul. 27, 2018
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Total revenues			$ 3,985	$ 3,413	$ 8,116	$ 6,901
Patent Purchase Agreement with Indivior [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Upfront non-refundable payment received	$ 12,500
Granted patents extending year, minimum	2026
Patent Purchase Agreement with Indivior [Member] \| Intellectual Property Rights [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Total revenues		$ 12,500						$ 12,500
Patent Purchase Agreement with Indivior [Member] \| Regulatory Based Milestone [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Performance milestone payments based on successful development	$ 5,000								$ 5,000
Revenue recognition milestone achieved							$ 5,000