SCHEDULE 13G/A 0001104659-24-024904 0000904589 XXXXXXXX LIVE 2 Common Stock, par value $0.0001 per share 12/31/2024 0001082038 Durect Corp. 266605500 10240 Bubb Road Cupertino CA 95014-1417 Rule 13d-1(c) R. Scott Asen X1 2580000.00 500000.00 2580000.00 500000.00 3080000.00 N 9.92 IN * Includes 30,000 shares held by a certain charitable foundation of which the Reporting Person is a trustee. The other trustee has designated investment authority for the foundation to the Reporting Person. The Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest (see Item 4). ** Consists of shares held by certain Managed Accounts, as to which the Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest (see Item 4). Durect Corp. 10240 Bubb Road Cupertino, CA 95014-1417 R. Scott Asen (the "Reporting Person") Asen and Co. 222 1/2 East 49th Street New York, New York 10017 The Reporting Person is a citizen of the United States of America. Y The Reporting Person directly owns 2,550,000 shares. The Reporting Person is a trustee of The Asen Foundation (the "Foundation"), a not-for-profit foundation which owns 30,000 shares, and has been delegated investment authority for the Foundation by the other trustee of the Foundation. The Reporting Person is the President of Asen and Co., which provides certain advisory services to accounts (the "Managed Accounts") that own 500,000 shares. The Reporting Person may be deemed to beneficially own the shares held by the Foundation and by the Managed Accounts, but the Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest. 9.92%, consisting of: (1) 2,550,000 shares owned directly by the Reporting Person, which represent approximately 8.21% of the issued and outstanding shares of Common Stock of the Issuer, (2) 30,000 shares owned by the Foundation, which represent approximately 0.10% of the issued and outstanding shares of Common Stock of the issuer and (3) 500,000 shares owned by the Managed Accounts, which represent approximately 1.61% of the issued and outstanding shares of Common Stock of the issuer. The foregoing percentages are calculated based on 31,041,981 shares of Common Stock outstanding as of September 30, 2024, as reported in the issuer's quarterly report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2024. The Reporting Person has sole voting power over 2,550,000 shares which he owns directly including through a revocable trust and IRA account. The Reporting Person has sole voting power over 30,000 shares which are owned by the Foundation and as to which the Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest. The Reporting Person has shared voting power over 500,000 shares owned by the Managed Accounts. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest. The Reporting Person has sole voting power over 2,550,000 shares which he owns directly including through a revocable trust and IRA account. The Reporting Person has sole voting power over 30,000 shares which are owned by the Foundation and as to which the Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest. The Reporting Person has shared voting power over 500,000 shares owned by the Managed Accounts. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest. Y N See response to Item 4. Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. R. Scott Asen /s/ R. Scott Asen 01/07/2025