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Stock-Based Compensation (Tables)
 12 Months Ended
Dec. 31, 2013
Stock-Based Compensation  
Schedule of stock-based compensation expense included in the consolidated statements of operations
  Year Ended December 31,  
(In thousands)
  2013   2012   2011  

Research and development

   $ 16,017   $ 13,667   $ 13,422  

Selling, general and administrative

     9,670     10,116     11,494  
               
​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​

Total stock-based compensation expense

   $ 25,687   $ 23,783   $ 24,916  
               
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Schedule of stock-based compensation expense by award type included in the consolidated statements of operations
  Year Ended December 31,  
(In thousands)
  2013   2012   2011  

Employee stock options

   $ 4,132   $ 3,417   $ 4,528  

Employee RSUs

     10,174     10,803     10,876  

Employee RSAs

     9,723     7,602     5,498  

Employee performance RSUs

     61     743     2,414  

Employee performance RSAs

     1,061     366     —  

Non-employee options and RSUs

     —     —     307  

ESPP

     536     852     1,293  
               
​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​

Total stock-based compensation expense

   $ 25,687   $ 23,783   $ 24,916  
               
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Schedule of unrecognized compensation cost, net of expected forfeitures, and the estimated weighted-average amortization period, using the straight-line attribution method

     As of December 31, 2013, the unrecognized stock-based compensation cost, net of expected forfeitures, and the estimated weighted-average amortization period, using the straight-line attribution method, was as follows:

(In thousands, except amortization period)
  Unrecognized
Compensation
Cost		   Weighted-average
amortization
period (years)		  

Stock options

   $ 16, 916     3.1  

RSUs

     15,473     2.4  

RSAs

     23,296     2.5  

Performance RSUs

     4     0.1  

Performance RSAs

     627     2.9  
             
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Total unrecognized stock-based compensation expense

   $ 56,316        
             
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Summary of equity award activity under the 2012 plan and prior plans

 

(In thousands, except per share data)
   Number of
Shares
Subject to
Outstanding
Options		   Weighted-
average
Exercise Price
of
Outstanding
Options		   Number of
Shares
Subject to
Outstanding
RSUs		   Weighted-
average
Fair Value
per
Share at
Grant		   Number of
Shares
Outstanding
Subject to
Vesting or
Performance
Conditions
with
Vesting		   Weighted-
average
Fair Value
per
Share at
Grant		  

Balance at December 31, 2010

     7,654   $ 16.91     1,897   $ 12.45     33   $ 26.10  

Granted

     629     21.98     471     24.96     2,483     24.61  

Exercised

     (1,265 )   8.87     —     —     —     —  

Released RSUs/RSAs

     —     —     (797 )   13.89     (74 )   24.96  

Forfeited

     (127 )   29.15     (29 )   15.35     —     —  
                                 
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Balance at December 31, 2011

     6,891     18.62     1,542     15.47     2,442     24.62  

Granted

     335     21.91     528     18.45     447     18.11  

Exercised

     (947 )   7.98     —     —     —     —  

Released RSUs/RSAs

     —     —     (752 )   14.19     (388 )   24.77  

Forfeited

     (159 )   24.43     (78 )   18.48     —     —  
                                 
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Balance at December 31, 2012

     6,120     20.30     1,240     17.32     2,501     23.43  

Granted

     820     35.54     572     23.47     510     23.25  

Exercised

     (1,977 )   14.04     —     —     —     —  

Released RSUs/RSAs

     —     —     (630 )   15.38     (452 )   21.64  

Forfeited

     (139 )   25.69     (67 )   18.14     (194 )   24.37  
                                 
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Balance at December 31, 2013

     4,824     25.30     1,115     21.53     2,365     23.66  
                                 
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Schedule of weighted-average assumptions used to estimate the fair value of stock options granted and employee stock purchase plan issuances
  Year Ended December 31,
 
   2013   2012   2011

Employee stock options

            

Risk-free interest rate

   0.76% - 2.02%   0.74% - 1.17%   1.10% - 2.57%

Expected life (in years)

   5 - 6   5 - 6   5 - 6

Volatility

   58% - 60%   55% - 60%   49% - 55%

Dividend yield

   —%   —%   —%

Weighted-average estimated fair value of stock options granted

   $19.96   $11.50   $11.11

Employee stock purchase plan issuances

            

Risk-free interest rate

   0.09% - 0.26%   0.14% - 0.29%   0.05% - 0.54%

Expected life (in years)

   0.5 - 2   0.5 - 2   0.5 - 2

Volatility

   56% - 61%   51% - 64%   48% - 59%

Dividend yield

   —%   —%   —%

Weighted-average estimated fair value of ESPP issuances

   $16.44   $8.07   $9.46
Schedule of outstanding options to purchase common stock based on range of stock option exercise prices

As of December 31, 2013, all outstanding options to purchase our common stock are summarized in the following table (in thousands, except years and per share data):

 
   Options Outstanding   Options Exercisable  
Range of Exercise Prices
  Number
Outstanding		   Weighted-
average
Remaining
Contractual
Life in Years		   Weighted-
average
Exercise
Prices		   Options
Exercisable		   Weighted-
average
Remaining
Contractual
Life in Years		   Weighted-
average
Exercise
Price		  

$3.10 - $9.69

     280     0.5   $ 8.99     280     0.5   $ 8.99  

$9.70 - $16.00

     557     3.1     14.77     551     3.1     14.80  

$16.01 - $19.80

     936     3.8     18.26     785     3.1     18.24  

$19.81 - $24.71

     467     6.7     22.08     271     5.6     22.00  

$24.72 - $29.70

     987     3.2     28.23     939     2.9     28.31  

$29.71 - $35.00

     916     3.6     33.34     893     3.4     33.39  

$35.01 - $41.53

     681     9.7     37.46     8     3.1     35.46  
                                   
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Total

     4,824     4.5     25.30     3,727     3.1     23.51  
                                   
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