Debt - Convertible Subordinated Notes (Details)				1 Months Ended		3 Months Ended			6 Months Ended
	Apr. 18, 2022 USD ($)	Mar. 07, 2022 USD ($)	Jul. 31, 2014 $ / shares $ / Item	Jul. 31, 2014 $ / shares $ / Item shares	Jan. 31, 2013 USD ($) Item $ / shares $ / Item shares	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Apr. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2016 USD ($)
Debt
Payment for repurchase of debt instrument									$ 165,131,000	$ 0
Accrued interest payable						$ 4,498,000			4,498,000			$ 4,152,000
Loss on extinguishment of debt						0		$ 0	(20,662,000)	0
Liability component
Principal						549,704,000			549,704,000			433,484,000
Debt discount and issuance costs, net						(10,454,000)			$ (10,454,000)			(38,831,000)
Convertible subordinated notes | Privately-negotiated capped call option
Debt
Cap price for the underlying number of shares (in dollars per share) | $ / Item			27.04	27.04
2023 Notes | Convertible subordinated notes
Debt
Loan amount					$ 287,500,000
Debt instrument maturity date					Jan. 15, 2023
Proceeds from issuance of notes payable, net of debt issuance costs					$ 281,200,000
Debt Instrument, annual interest rate					2.125%
Initial conversion, shares per $1,000 principal amount | shares | shares					35.9903
Adjusted conversion, shares per $1,000 principal amount | shares				50.5818
Conversion price of convertible notes into common stock (in dollars per share) | $ / shares			$ 19.77	$ 19.77	$ 27.79
Ratio of repurchase price to the principal amount									100.00%
Portion of debt retired, face value		$ 144,800,000					$ 144,800,000						$ 14,100,000
Portion of debt retired, carrying value							144,500,000						$ 13,900,000
Payment for repurchase of debt instrument		$ 165,600,000					$ 165,600,000
Percentage of notes repurchased		60.00%
Accrued interest payable		$ 400,000
Unamortized debt issuance cost		300,000
Loss on extinguishment of debt		$ 20,700,000
Effective interest rate		2.37%
Liability component
Principal	$ 96,200,000	$ 96,200,000				96,204,000			$ 96,204,000			240,984,000
Debt discount and issuance costs, net						(132,000)			(132,000)		$ (200,000)	(620,000)
Net Carrying Amount						96,072,000			96,072,000			$ 240,364,000
Interest expense
Contractual interest expense						511,000		1,280,000	1,595,000	2,560,000
Amortization of debt issuance costs						59,000		147,000	181,000	288,000
Total interest and amortization expense						$ 570,000		$ 1,427,000	$ 1,776,000	$ 2,848,000
2023 Notes | Convertible subordinated notes | Privately-negotiated capped call option
Debt
Payments for capped call options					$ 36,800,000
Number of derivative instruments purchased | Item					2
Strike price for the underlying number of shares (in dollars per share) | $ / shares			$ 27.79	$ 19.77	$ 27.79
Cap price for the underlying number of shares (in dollars per share) | $ / Item			38.00	38.00	38.00
2023 Notes | Convertible subordinated notes | Stock prices below $27.79 per share | Minimum
Debt
Net shares settlement payable to the entity | shares					0
2023 Notes | Convertible subordinated notes | Stock prices above $38.00 per share | Maximum
Debt
Net shares settlement payable to the entity | shares					2,779,659
Innoviva's Common Stock | 2023 Notes | Convertible subordinated notes
Liability component
Notes converted into common stock, Amount	$ 3,000.0