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Financial Instruments and Fair Value Measurements - Equity Investment in ImaginAb (Details)
$ in Thousands
3 Months Ended
Mar. 31, 2021
USD ($)
shares
Jun. 30, 2022
USD ($)
Director
Dec. 31, 2021
USD ($)
Equity Investment      
Equity and long-term investments   $ 494,097 $ 483,845
ImaginAb      
Equity Investment      
Transaction costs to acquire equity securities $ 400    
Equity investment ownership percentage   14.40% 14.50%
Number of Investee's Board members currently representing the Company | Director   1  
Number of the Investee's Board members | Director   5  
Equity and long-term investments at fair value   $ 6,400 $ 6,400
ImaginAb | Series C preferred stock      
Equity Investment      
Number of shares to be purchased under the securities purchase agreement | shares 4,051,724    
Amount of securities purchase agreement $ 4,700    
ImaginAb | One of ImaginAb's Common Stockholders | Common stock      
Equity Investment      
Number of shares to be purchased under the securities purchase agreement | shares 4,097,157    
Amount of securities purchase agreement $ 1,300