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Other Financial Information (Property, Plant, & Equipment) (Details) (USD $)
9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Dec. 31, 2012
Property, Plant and Equipment [Line Items]      
Property, plant and equipment, gross $ 86,280,000   $ 78,993,000
Less accumulated depreciation and amortization (56,373,000)   (45,499,000)
Total 29,907,000   33,494,000
Depreciation expense 11,000,000 7,400,000  
Building and Improvements
     
Property, Plant and Equipment [Line Items]      
Property, plant and equipment, gross 8,687,000   8,660,000
Laboratory Equipment
     
Property, Plant and Equipment [Line Items]      
Property, plant and equipment, gross 48,362,000   42,846,000
Leasehold Improvements
     
Property, Plant and Equipment [Line Items]      
Property, plant and equipment, gross 8,122,000   7,950,000
Office Furniture and Equipment
     
Property, Plant and Equipment [Line Items]      
Property, plant and equipment, gross 21,109,000   19,537,000
Capital lease obligations $ 400,000   $ 400,000