Condensed Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Sep. 30, 2013	Dec. 31, 2012
Assets
Cash and cash equivalents	$ 38,752	$ 123,802
Marketable securities	45,961	52,140
Accounts receivable, net	8,620	7,887
Inventories	20,234	10,570
Other current assets and prepaid expenses	4,194	3,075
Total current assets	117,761	197,474
Property, equipment and leasehold improvements, net	29,907	33,494
Goodwill	10,007	10,007
Other assets	7,149	7,980
Total assets	164,824	248,955
Liabilities and stockholders' equity
Accounts payable	15,403	16,469
Accrued expenses	24,832	24,507
Long-term debt and obligations, current portion	7,631	7,601
Other current liabilities	4,341	2,713
Total current liabilities	52,207	51,290
Long-term debt and obligations, less current portion	11,516	17,041
5.00% Convertible Senior Notes due 2017	130,000	130,000
Other long-term liabilities	2,130	2,617
Commitments and contingencies
Stockholders' equity:
Convertible preferred stock, par value $0.001; 5,000 shares authorized, no shares issued or outstanding at September 30, 2013 and December 31, 2012	0	0
Common stock, par value $0.001; 185,000 shares authorized, 115,717 and 114,787 shares issued and outstanding at September 30, 2013 and December 31, 2012, respectively	116	115
Additional paid-in capital	963,705	954,372
Accumulated other comprehensive income	584	423
Accumulated deficit	(995,434)	(906,903)
Total stockholders' equity (deficit)	(31,029)	48,007
Total liabilities and stockholders' equity (deficit)	$ 164,824	$ 248,955