<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001137439-25-000639</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002044285</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>American Depository Shares</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001075880</issuerCik>
        <issuerName>KAZIA THERAPEUTICS LTD</issuerName>
        <issuerCusip>48669G105</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>Three International Towers, Level 24</com:street1>
          <com:street2>300 Barangaroo Avenue</com:street2>
          <com:city>SYDNEY NSW</com:city>
          <com:stateOrCountry>C3</com:stateOrCountry>
          <com:zipCode>2000</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Dauntless Investment Group, LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>176822.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>176822.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.9</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>Single Family Office/Passive Investor</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>KAZIA THERAPEUTICS LTD</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>Three International Towers, Level 24, 300 Barangaroo Avenue, SYDNEY NSW, AUSTRALIA, 2000.</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Dauntless Investment Group, LLC</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>3283 Foxfire Dr., Milford, MI 48380</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Delaware</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>176,822

The reporting person?s ownership consists of (i) 144,595 American Depository Shares and (ii) 32,227 Pre-funded Warrants; however, due to the exercise limitations of the Pre-funded Warrants, the reporting person?s beneficial ownership has been limited to 176,822 shares in the aggregate.</amountBeneficiallyOwned>
        <classPercent>9.99%

Each of the Pre-funded Warrants includes a provision limiting the holder?s ability to exercise the Pre-funded Warrants if such exercise would cause the holder to beneficially own greater than 9.99% of Kazia Therapeutics Limited.

</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>176,822</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Dauntless Investment Group, LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/Matthew Okkerse</signature>
        <title>CFO</title>
        <date>11/13/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
