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14. Stock-Based Compensation (Details 2) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Number of Shares    
Outstanding 2,147,561 2,130,239
Granted 2,578,000 498,000
Exercised (26,865) (28,418)
Cancelled/forfeited (317,998) (452,260)
Outstanding 4,380,698 2,147,561
Shares vested and expected to vest 4,052,341  
Exercisable 2,716,262 1,351,894
Weighted-Average Exercise Price    
Outstanding $ 3.78 $ 3.96
Granted 1.50 3.18
Exercised 1.85 2.44
Cancelled/forfeited 2.16 4.05
Outstanding 2.56 3.78
Shares vested and expected to vest 2.56  
Exercisable $ 3.04 $ 4.18
Weighted-Average Remaining Contract Life    
Outstanding 6 years 10 months 24 days 8 years
Outstanding 6 years 2 months 12 days 6 years 10 months 24 days
Shares vested and expected to vest 6 years 2 months 12 days  
Exercisable 6 years 1 month 6 days 6 years 7 months 6 days
Aggregate Intrinsic Value    
Outstanding $ 0 $ 482
Outstanding 0 0
Shares vested and expected to vest 0  
Exercisable $ 0 $ 0