X0306 4 2020-10-08 0 0001720725 Oyster Point Pharma, Inc. OYST 0001072501 ATIEH MICHAEL G C/O OYSTER POINT PHARMA, INC. 202 CARNEGIE CENTER, SUITE 109 PRINCETON NJ 08540 1 0 0 0 Common Stock 2020-10-08 4 A 0 15295 0.00 A 15295 D Common Stock 2020-10-08 4 A 0 4400 0.00 A 19695 D This security represents restricted stock units (the "RSUs"). Each RSU represents a contingent right to received one share of common stock of the Issuer. 1/3 of the RSUs will vest in three equal annual installments, with 1/3 vesting on the one (1) year anniversary of October 8, 2020, and one-third (1/3) of the RSUs vesting annually thereafter on October 8, subject to the Reporting Person continuing to be a service provider pursuant to the terms of the Issuer's 2019 Equity Incentive Plan through each such date. 1/8 of the RSUs will vest in eight equal monthly installments beginning on the first month following the grant date on the same day of the month until the Company's Annual Meeting of Stockholders to be held in 2021; provided, however, if all of such RSUs are not fully vested at the Company's next Annual Meeting of Stockholders, any such remaining RSUs will vest on such date, in each case, subject to the Reporting Person continuing to be a service provider pursuant to the terms of the Issuer's 2019 Equity Incentive Plan through each such date. /s/ Shashi Khiani, Attorney-in-Fact 2020-10-13