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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001181431-04-059883.txt : 20041220
<SEC-HEADER>0001181431-04-059883.hdr.sgml : 20041220
<ACCEPTANCE-DATETIME>20041220180507
ACCESSION NUMBER:		0001181431-04-059883
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20041216
FILED AS OF DATE:		20041220
DATE AS OF CHANGE:		20041220

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CENTENE CORP
		CENTRAL INDEX KEY:			0001071739
		STANDARD INDUSTRIAL CLASSIFICATION:	HOSPITAL & MEDICAL SERVICE PLANS [6324]
		IRS NUMBER:				041406317

	BUSINESS ADDRESS:	
		STREET 1:		7711 CARONDELET AVE
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63105
		BUSINESS PHONE:		3147254477

	MAIL ADDRESS:	
		STREET 1:		7711 CARONDELET AVE
		STREET 2:		SUITE 800
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63105

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BRADT SAMUEL E
		CENTRAL INDEX KEY:			0001205256

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-31826
		FILM NUMBER:		041215287

	MAIL ADDRESS:	
		STREET 1:		6925 WILDWOOD POINT RD
		CITY:			CHENEQUA
		STATE:			WI
		ZIP:			53029
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd61915.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2004-12-16</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001071739</issuerCik>
        <issuerName>CENTENE CORP</issuerName>
        <issuerTradingSymbol>CNC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001205256</rptOwnerCik>
            <rptOwnerName>BRADT SAMUEL E</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>7711 CARONDELET AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 800</rptOwnerStreet2>
            <rptOwnerCity>ST. LOUIS</rptOwnerCity>
            <rptOwnerState>MO</rptOwnerState>
            <rptOwnerZipCode>63105</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2004-12-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>30000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>29.34</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>13960</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Mr. Bradt contributed 15,000 shares of CNC common stock to an exchange fund in exchange for shares of the exchange fund.  The CNC common stock was valued at $58.67 per share for the purpose of determining the number of shares of the exchange fund issuable to Mr. Bradt.  By factoring in the 2 for 1 stock split paid on December 17, 2004, Mr. Bradt effectively exchanged 30,000 shares of CNC common stock at $29.34 per share for shares of the exchange fund.</footnote>
        <footnote id="F2">Shares beneficially owned as of December 20, 2004 include shares received December 17, 2004 from a 2 for 1 stock split.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Karey L. Witty (executed by attorney-in-fact)</signatureName>
        <signatureDate>2004-12-20</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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