Exhibit 23

Consent of Independent Registered Public Accounting Firm

The Board of Directors

Centene Corporation:

We consent to the incorporation by reference in the registration statements on Form S-8 (Nos. 333-236036, 333‑217634, 333-210376, 333-197737, 333-180976, 333-108467, and 333-90976) and in the registration statement on Form S-3 (No. 333-217636) of Centene Corporation of our reports dated February 18, 2020, with respect to the consolidated balance sheets of Centene Corporation and subsidiaries as of December 31, 2019 and 2018, the related consolidated statements of operations, comprehensive earnings, stockholders’ equity, and cash flows for each of the years in the three-year period ended December 31, 2019 and the related notes (collectively, the consolidated financial statements), and the effectiveness of internal control over financial reporting as of December 31, 2019, which reports appear in the December 31, 2019 annual report on Form 10‑K of Centene Corporation.

/s/ KPMG LLP

St. Louis, Missouri

February 18, 2020