CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Income Statement [Abstract]
Product revenue	$ 27,470	$ 20,453
Cost of sales	4,331	3,722
Gross profit	23,139	16,731
Operating expenses:
Research and development	14,019	16,552
Selling, general and administrative	20,388	14,839
Impairment of IPR&D	39,600
Change in fair value of contingent consideration related to Quinsair acquisition	(14,730)
Total operating expenses	59,277	31,391
Loss from operations	(36,138)	(14,660)
Interest income	132	27
Interest expense	(5,018)	(4,498)
Foreign currency transaction loss	(213)	(476)
Adjustment to fair value of common stock warrants		(55)
Loss before provision for income taxes	(41,237)	(19,662)
Provision for income taxes	348	21
Net Loss	(41,585)	(19,683)
Other comprehensive income (loss):
Foreign currency translation gain (loss), net of tax	43	(547)
Comprehensive Loss	$ (41,542)	$ (20,230)
Net loss per share:
Basic and diluted	$ (0.49)	$ (0.28)
Weighted-average shares outstanding:
Basic and diluted	85,255,212	69,140,642