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Consolidated Statement of Stockholders' Equity (Deficit) (USD $)
Share data in Thousands
Common Stock [Member]
Additional Paid-In Capital [Member]
Receivable from Stockholders [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Deficit Accumulated During Development Stage [Member]
Total
Balance at Sep. 07, 2005 $ 1,000 $ 9,000 $ (10,000)   $ 0 $ 0
Balance (in shares) at Sep. 07, 2005 1,399          
Common stock issued in May 2006 at $0.43 per share pursuant to a stock purchase agreement dated February 2006 500 99,500 (100,000)   0 0
Common stock issued in May 2006 at $0.43 per share pursuant to a stock purchase agreement dated February 2006 (in shares) 233          
Common stock issued in May 2006 at $0.86 per share pursuant to a stock purchase agreement dated February 2006 500 199,500 0   0 200,000
Common stock issued in May 2006 at $0.86 per share pursuant to a stock purchase agreement dated February 2006 (in shares) 233          
Common stock issued on May 25, 2006 at $2.57 per share, net of fundraising costs of $218 2,000 4,780,000 0   0 4,782,000
Common stock issued on May 25, 2006 at $2.57 per share, net of fundraising costs of $218 (in shares) 1,943          
Common stock and warrants issued for a placement fee in connection with May 25, 2006 financing 0 0 0   0 0
Common stock and warrants issued for a placement fee in connection with May 25, 2006 financing (in shares) 186          
Common stock issued in connection with reverse merger in May 2006 3,000 (3,000) 0   0 0
Common stock issued in connection with reverse merger in May 2006 (in shares) 2,914          
Repayment of receivable from stockholders 0 0 110,000   0 110,000
Exercise of common stock options (in shares)           0
Consultant stock-based compensation expense 0 24,000 0   0 24,000
Net loss 0 0 0   (969,000) (969,000)
Balance at Aug. 31, 2006 7,000 5,109,000 0   (969,000) 4,147,000
Balance (in shares) at Aug. 31, 2006 6,908          
Exercise of common stock warrants 1,000 1,969,000     0 1,970,000
Exercise of common stock warrants (in shares) 766          
Exercise of common stock options 0 8,000     0 8,000
Exercise of common stock options (in shares) 3         3
Consultant stock-based compensation expense 0 96,000     0 96,000
Employee stock-based compensation expense 0 369,000     0 369,000
Net loss 0 0     (3,632,000) (3,632,000)
Balance at Aug. 31, 2007 8,000 7,551,000     (4,601,000) 2,958,000
Balance (in shares) at Aug. 31, 2007 7,677          
Exercise of common stock warrants 1,000 1,924,000     0 1,925,000
Exercise of common stock warrants (in shares) 748          
Exercise of common stock options (in shares)           0
Consultant stock-based compensation expense 0 240,000     0 240,000
Consultant stock based compensation expense (in shares) 2          
Employee stock-based compensation expense 0 492,000     0 492,000
Employee stock-based compensation expense (in shares) 23          
Issuance of common stock for loan placement fee 0 102,000     0 102,000
Issuance of common stock for loan placement fee (in shares) 47          
Issuance of common stock for the purchase of Convivia, Inc. assets 0 240,000     0 240,000
Issuance of common stock for the purchase of Convivia, Inc. assets (in shares) 102          
Issuance of common stock for the merger with Encode Pharmaceuticals, Inc. 0 2,658,000     0 2,658,000
Issuance of common stock for the merger with Encode Pharmaceuticals, Inc. (in shares) 803          
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs 5,000 9,051,000     0 9,056,000
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs (in shares) 4,662          
Net loss 0 0     (8,054,000) (8,054,000)
Balance at Aug. 31, 2008 14,000 22,258,000     (12,655,000) 9,617,000
Balance (in shares) at Aug. 31, 2008 14,064          
Exercise of common stock warrants 2,000 2,613,000     0 2,615,000
Exercise of common stock warrants (in shares) 2,032          
Exercise of common stock options (in shares)           0
Consultant stock-based compensation expense 0 48,000     0 48,000
Consultant stock based compensation expense (in shares) 0          
Employee stock-based compensation expense 0 354,000     0 354,000
Employee stock-based compensation expense (in shares) 23          
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs 2,000 2,091,000     0 2,093,000
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs (in shares) 1,738          
Net loss 0 0     (9,224,000) (9,224,000)
Balance at Aug. 31, 2009 18,000 27,364,000   0 (21,879,000) 5,503,000
Balance (in shares) at Aug. 31, 2009 17,857          
Exercise of common stock warrants 0 475,000   0 0 475,000
Exercise of common stock warrants (in shares) 197          
Exercise of common stock options 0 64,000   0 0 64,000
Exercise of common stock options (in shares) 38         38
Consultant stock-based compensation expense 0 78,000   0 0 78,000
Consultant stock based compensation expense (in shares) 0          
Employee stock-based compensation expense 0 217,000   0 0 217,000
Employee stock-based compensation expense (in shares) 12          
Common stock issued and warrants/options assumed with 2009 Merger 1,000 4,416,000   0 0 4,417,000
Common stock issued and warrants/options assumed with 2009 Merger (in shares) 941          
Issuance of common stock for the purchase of Convivia, Inc. assets           0
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs 5,000 13,598,000   0 0 13,603,000
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs (in shares) 4,898          
Issuance of common stock pursuant to an equity line facility at specified price net of fundraising costs and commitment shares 2,000 4,840,000   0 0 4,842,000
Issuance of common stock pursuant to an equity line facility at specified price net of fundraising costs and commitment shares (in shares) 2,387          
Issuance of common stock and warrants in a registered direct financing at $2.00 per unit, including placement agent warrants, net of fundraising costs of $1,247 4,000 6,243,000   0 0 6,247,000
Issuance of common stock and warrants in a registered direct financing at $2.00 per unit, including placement agent warrants, net of fundraising costs of $1,247 (in shares) 3,747          
Initial value of warrants issued in a registered direct financing 0 (1,864,000)   0 0 (1,864,000)
Initial value of warrants issued in 2010 private placement 0 (7,813,000)   0 0 (7,813,000)
Reclassification of the fair value of warrant liabilities upon exercise           0
Comprehensive loss 0 0   (8,000) (18,928,000) (18,936,000)
Foreign currency translation gain (loss)           (8,000)
Net loss           (18,928,000)
Balance at Aug. 31, 2010 30,000 47,618,000   (8,000) (40,807,000) 6,833,000
Balance (in shares) at Aug. 31, 2010 30,077          
Exercise of common stock warrants 4,000 8,909,000   0 0 8,913,000
Exercise of common stock warrants (in shares) 3,340          
Exercise of common stock options 0 96,000   0 0 96,000
Exercise of common stock options (in shares) 39         39
Consultant stock-based compensation expense 0 197,000   0 0 197,000
Consultant stock based compensation expense (in shares) 0          
Employee stock-based compensation expense 0 1,920,000   0 0 1,920,000
Employee stock-based compensation expense (in shares) 0          
Issuance of common stock pursuant to an equity line facility at specified price net of fundraising costs and commitment shares 2,000 6,571,000   0 0 6,573,000
Issuance of common stock pursuant to an equity line facility at specified price net of fundraising costs and commitment shares (in shares) 2,113          
Reclassification of the fair value of warrant liabilities upon exercise 0 8,506,000   0 0 8,506,000
Comprehensive loss           (37,185,000)
Foreign currency translation gain (loss) 0 0   10,000 0 10,000
Net loss 0 0   0 (37,195,000) (37,195,000)
Balance at Aug. 31, 2011 36,000 73,817,000   2,000 (78,002,000) (4,147,000)
Balance (in shares) at Aug. 31, 2011 35,569          
Exercise of common stock warrants 2,000 5,011,000   0 0 5,013,000
Exercise of common stock warrants (in shares) 1,831          
Exercise of common stock options 0 366,000   0 0 366,000
Exercise of common stock options (in shares) 160         160
Consultant stock-based compensation expense 0 72,000   0 0 72,000
Consultant stock based compensation expense (in shares) 0          
Employee stock-based compensation expense 0 4,487,000   0 0 4,487,000
Employee stock-based compensation expense (in shares) 0          
Reclassification of the fair value of warrant liabilities upon exercise 0 9,482,000   0 0 9,482,000
Issuance of common stock in a follow-on public offering at a specified price net of fundraising costs 12,000 42,822,000   0 0 42,834,000
Issuance of common stock in a follow-on public offering at a specified price net of fundraising costs (in shares) 11,500          
Issue of common stock pursuant to an at-the-market financing facility at a specified price net of fundraising costs 1,000 7,323,000   0 0 7,324,000
Issue of common stock pursuant to an at-the-market financing facility at a specified price net of fundraising costs (in shares) 1,508          
Comprehensive loss           (38,696,000)
Foreign currency translation gain (loss) 0 0   (52,000) 0 (52,000)
Net loss 0 0   0 (38,644,000) (38,644,000)
Balance at Aug. 31, 2012 51,000 143,380,000   (50,000) (116,646,000) 26,735,000
Balance (in shares) at Aug. 31, 2012 50,568          
Exercise of common stock warrants 0 1,843,000   0 0 1,843,000
Exercise of common stock warrants (in shares) 625          
Exercise of common stock options 0 192,000   0 0 192,000
Exercise of common stock options (in shares) 79         79
Consultant stock-based compensation expense 0 9,000   0 0 9,000
Consultant stock based compensation expense (in shares) 0          
Employee stock-based compensation expense 0 2,230,000   0 0 2,230,000
Employee stock-based compensation expense (in shares) 0          
Reclassification of the fair value of warrant liabilities upon exercise 0 2,345,000   0 0 2,345,000
Issue of common stock pursuant to an at-the-market financing facility at a specified price net of fundraising costs 1,000 5,946,000   0 0 5,947,000
Issue of common stock pursuant to an at-the-market financing facility at a specified price net of fundraising costs (in shares) 1,153          
Comprehensive loss           (19,357,000)
Foreign currency translation gain (loss) 0 0   (65,000) 0 (65,000)
Net loss 0 0   0 (19,292,000) (19,292,000)
Balance at Dec. 31, 2012 $ 52,000 $ 155,945,000   $ (115,000) $ (135,938,000) $ 19,944,000
Balance (in shares) at Dec. 31, 2012 52,425