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Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands, unless otherwise specified
4 Months Ended 12 Months Ended 88 Months Ended
Dec. 31, 2012
Aug. 31, 2012
Aug. 31, 2011
Aug. 31, 2010
Dec. 31, 2012
Cash flows from operating activities:          
Net loss $ (19,292) $ (38,644) $ (37,195) $ (18,928) $ (135,938)
Adjustments to reconcile net loss to net cash used in operating activities:          
Employee stock-based compensation expense 2,230 4,487 1,920 217 10,068
Consultant stock-based compensation expense 9 72 197 78 764
Fair value adjustment of common stock warrants 1,484 3,173 16,301 5,895 26,853
Amortization of intangible assets 49 146 153 152 746
Depreciation of fixed assets 42 65 78 72 608
Unrealized gain (loss) on short-term investments 64 0 0 0 64
Write-off of intangible assets and other intellectual property 0 900 108 0 1,249
Amortization of capitalized finder's fee 0 0 0 0 102
Capitalized acquisition costs previously expensed 0 0 0 0 38
Changes in assets and liabilities:          
Prepaid expenses and other 1,501 (2,695) (130) (79) (1,510)
Intangible assets 0 0 0 0 (150)
Deposits 79 0 (2) (3) (26)
Accounts payable 3,081 754 210 24 4,682
Accrued liabilities (502) 403 1,119 (2) 1,470
Deferred rent (8) (10) 22 3 6
Net cash used in operating activities (11,263) (31,349) (17,219) (12,571) (90,974)
Cash flows from investing activities:          
Purchase of fixed assets (55) (378) (50) 581 581
Cash acquired in 2009 Merger 0 0 0 (20) (980)
Purchase of short-term investments (6,853) (45,307) 0 0 (52,160)
Sale of short-term investments   30,000 0 0 30,000
Change in restricted cash 6 (54) (114) 0 (163)
Net cash used in investing activities (6,902) (15,739) (164) 561 (22,722)
Cash flows from financing activities:          
Proceeds from the sale of common stock 0 46,000 0 22,555 85,941
Proceeds from the sale of common stock under an equity line 0 0 6,740 4,900 11,640
Proceeds from the sale of common stock under an ATM agreement 6,157 7,684 0 0 13,841
Proceeds from the exercise of common stock warrants 1,843 5,013 8,913 475 22,754
Proceeds from the exercise of common stock options 192 366 96 64 727
Proceeds from note payable 25,000 0 0 0 25,000
Fundraising costs (210) (3,528) 0 (2,720) (8,065)
Deferred offering costs 25 18 (152) 0 43
Proceeds from the sale of common stock to initial investors 0 0 0 0 310
Debt issuance costs (1,959) 0 0 0 (1,959)
Principal payments on capital lease (2) (5) (5) (4) (25)
Interest payment on note payable (83) 0 0 0 (83)
Net cash provided by financing activities 30,963 55,548 15,592 25,270 150,124
Foreign currency translation adjustment (65) (52) 10 (8) (115)
Net increase (decrease) in cash and cash equivalents 12,733 8,408 (1,781) 13,252 36,313
Cash and cash equivalents, beginning of period 23,580 15,172 16,954 3,702 0
Cash and cash equivalents, end of period 36,313 23,580 15,172 16,954 36,313
Supplemental cash flow information:          
Interest Paid 83 3 2 4 100
Supplemental disclosure of non-cash financing activities:          
Warrants issued in connection with financings       9,677 16,310
Initial fair value of warrants issued to placement agents in connection with financings       209 209
Common stock and warrants issued in connection with reverse merger       4,417 4,417
Common stock issued as fee for equity line 0 0 519 309 828
Fair value of warrant liability reclassified to equity upon exercise 2,345 9,482 8,506 0 20,333
Acquisition of equipment in exchange for capital lease 0 13 14 0 48
Notes receivable issued in exchange for common stock       0 110
Common stock issued for a finder's fee       0 102
Common stock issued in asset purchase         $ 2,899