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Consolidated Statements of Stockholders' Equity (Deficit) (USD $)
In Thousands, except Share data
Common Stock
Additional Paid-In capital
Receivable From Stockholders
Accumulated Other Comprehensive Loss
Retained Earnings [Member]
Total
Beginning Balance, Amount at Sep. 07, 2005 $ 1,399          
Beginning Balance, Shares at Sep. 07, 2005 1 9 (10)   0 0
Common stock issued for cash 12 7,770 (100)   0 4,982
Common stock issued for cash (in shares) 2,409          
Common stock and warrants issued for a placement fee in connection with May 25, 2006 financing 0 0 0   0 0
Common stock and warrants issued for a placement fee in connection with May 25, 2006 financing (in shares) 186          
Common stock issued in connection with reverse merger in May 2006 3 (3) 0   0 0
Common stock issued in connection with reverse merger in May 2006 (in shares) 2,914          
Repayment of receivable from stockholders 0 0 110   0 110
Consultant stock-based compensation expense 0 24 0   0 24
Net loss 0 0 0   (969) (969)
Ending Balance, Amount at Aug. 31, 2006 7 5,109 0   (969) 4,147
Ending Balance, Shares at Aug. 31, 2006 6,908          
Exercise of common stock warrants, Shares 766          
Exercise of common stock warrants, Amount 1 1,969     0 1,970
Exercise of common stock options, Shares 3          
Exercise of common stock options, Amount 0 8     0 8
Employee stock-based compensation expense 0 369     0 369
Consultant stock-based compensation expense 0 0     0 96
Net loss 0 0     (3,632) (3,632)
Ending Balance, Amount at Aug. 31, 2007 8 7,551     (4,601) 2,958
Ending Balance, Shares at Aug. 31, 2007 7,677          
Exercise of common stock warrants, Shares 748          
Exercise of common stock warrants, Amount 1 1,924     0 1,925
Employee stock-based compensation expense, Shares 23          
Employee stock-based compensation expense 0 492     0 492
Consultant stock-based compensation expense, Shares 2          
Consultant stock-based compensation expense 0 240     0 240
Issuance of common stock for loan placement fee 0 102     0 102
Issuance of common stock for loan placement fee (in shares) 47          
Issuance of common stock for the purchase of Convivia, Inc. assets 0 240     0 240
Issuance of common stock for the purchase of Convivia, Inc. assets (in shares) 102          
Issuance of common stock for the merger with Encode Pharmaceuticals, Inc. 0 2,658     0 2,658
Issuance of common stock for the merger with Encode Pharmaceuticals, Inc. (in shares) 803          
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs 5 9,051     0 9,056
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs (in shares) 4,662          
Net loss 0 0     (8,054) (8,054)
Ending Balance, Amount at Aug. 31, 2008 14 22,258     (12,655) 9,617
Ending Balance, Shares at Aug. 31, 2008 14,064          
Exercise of common stock warrants, Shares 2,032          
Exercise of common stock warrants, Amount 2 2,613     0 2,615
Employee stock-based compensation expense, Shares 23          
Employee stock-based compensation expense 0 354     0 354
Consultant stock-based compensation expense, Shares 0          
Consultant stock-based compensation expense 0 48     0 48
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs 2 2,091     0 2,093
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs (in shares) 1,738          
Net loss 0 0 0   (9,224) (9,224)
Ending Balance, Amount at Aug. 31, 2009 18 27,364     (21,879) 5,503
Ending Balance, Shares at Aug. 31, 2009 17,857          
Exercise of common stock warrants, Shares 197          
Exercise of common stock warrants, Amount 0 475   0 0 475
Exercise of common stock options, Shares 38          
Exercise of common stock options, Amount 0 64   0 0 64
Employee stock-based compensation expense, Shares 12          
Employee stock-based compensation expense 0 217   0 0 217
Consultant stock-based compensation expense, Shares 0          
Consultant stock-based compensation expense 0 78   0 0 78
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs 5 13,598   0 0 13,603
Issuance of common stock and warrants under private placement at specified price including placement agent warrants net of fundraising costs (in shares) 4,898          
Common stock issued and warrants/options assumed with 2009 Merger, Shares 941          
Common stock issued and warrants/options assumed with 2009 Merger 1 4,416   0 0 4,417
Issuance of common stock to LPC pursuant to an equity line facility at a specified purchase price, net of fundraising costs and commitment shares totaling $533, Shares 2,387          
Issuance of common stock to LPC pursuant to an equity line facility at a specified purchase price, net of fundraising costs and commitment shares totaling $533 2 4,840   0 0 4,842
Issuance of common stock and warrants in a registered direct financing at $2.00 per unit, including placement agent warrants, net of fundraising costs of $1,247, Shares 3,747          
Issuance of common stock and warrants in a registered direct financing at $2.00 per unit, including placement agent warrants, net of fundraising costs of $1,247 4 6,243   0 0 6,247
Initial value of warrants issued in a registered direct financing 0 (1,864)   0 0 (1,864)
Initial value of warrants issued in 2010 private placement 0 (7,813)   0 0 (7,813)
Foreign currency translation loss           (8)
Comprehensive loss 0 0   (8) (18,928) (18,936)
Net loss           (18,928)
Ending Balance, Amount at Aug. 31, 2010 30 47,618   (8) (40,807) 6,833
Ending Balance, Shares at Aug. 31, 2010 30,077          
Exercise of common stock warrants, Shares 3,340          
Exercise of common stock warrants, Amount 4 8,909   0 0 8,913
Exercise of common stock options, Shares 39          
Exercise of common stock options, Amount 0 96   0 0 96
Employee stock-based compensation expense, Shares 0          
Employee stock-based compensation expense 0 1,920   0 0 1,920
Consultant stock-based compensation expense, Shares 0          
Consultant stock-based compensation expense 0 197   0 0 197
Issuance of common stock to LPC pursuant to an equity line facility at a specified purchase price, net of fundraising costs and commitment shares totaling $533, Shares 2,113          
Issuance of common stock to LPC pursuant to an equity line facility at a specified purchase price, net of fundraising costs and commitment shares totaling $533 2 6,571   0 0 6,573
Reclassification of the fair value of warrant liabilities 0 8,506   0 0 8,506
Foreign currency translation loss 0 0   10 0 10
Comprehensive loss           (37,185)
Net loss 0 0   0 (37,195) (37,195)
Ending Balance, Amount at Aug. 31, 2011 36 73,817   2 (78,002) (4,147)
Ending Balance, Shares at Aug. 31, 2011 35,569          
Exercise of common stock warrants, Shares 1,831          
Exercise of common stock warrants, Amount 2 5,011   0 0 5,013
Exercise of common stock options, Shares 160          
Exercise of common stock options, Amount 0 366   0 0 366
Employee stock-based compensation expense, Shares 0          
Employee stock-based compensation expense 0 4,487   0 0 4,487
Consultant stock-based compensation expense, Shares 0          
Consultant stock-based compensation expense 0 72   0 0 72
Issuance of common stock under an at-the-market sales agreement, net of commissions, Shares 1,508          
Issuance of common stock under an at-the-market sales agreement, net of commissions, Amount 1 7,323   0 0 7,324
Reclassification of the fair value of warrant liabilities 0 9,482   0 0 9,482
Issuance of common stock in a follow-on public offering at a $4.00 per share purchase price, net of fundraising costs totaling $3,168, Shares 11,500          
Issuance of common stock in a follow-on public offering at a $4.00 per share purchase price, net of fundraising costs totaling $3,168 12 42,822   0 0 42,834
Foreign currency translation loss 0 0   (52) 0 (52)
Comprehensive loss           (38,696)
Net loss 0 0 0 0 (38,644) (38,644)
Ending Balance, Amount at Aug. 31, 2012 51 143,380 0 (50) (116,646) 26,735
Ending Balance, Shares at Aug. 31, 2012 50,568          
Exercise of common stock warrants, Shares 625          
Exercise of common stock warrants, Amount 0 1,843   0 0 1,843
Exercise of common stock options, Shares 79          
Exercise of common stock options, Amount 0 192   0 0 192
Employee stock-based compensation expense 0 2,230   0 0 2,230
Consultant stock-based compensation expense, Shares 0          
Consultant stock-based compensation expense 0 9   0 0 9
Issuance of common stock under an at-the-market sales agreement, net of commissions, Shares 1,153          
Issuance of common stock under an at-the-market sales agreement, net of commissions, Amount 1 5,946   0 0 5,947
Reclassification of the fair value of warrant liabilities 0 2,345   0 0 2,345
Foreign currency translation loss 0 0   (65) 0 (65)
Comprehensive loss           (19,357)
Net loss 0 0   0 (19,292) (19,292)
Ending Balance, Amount at Dec. 31, 2012 $ 52 $ 155,945   $ (115) $ (135,938) $ 19,944
Ending Balance, Shares at Dec. 31, 2012 52,425