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11. Warrants (Tables)
4 Months Ended
Dec. 31, 2012
Warrants Tables  
Schedule of common stock warrants outstanding
    Number of
shares
exercisable
    Exercise
price
  Expiration date
Issued in connection with Encode merger     233     $ 2.87   12/13/2015
Issued to placement agents in May / June 2008     433     $ 2.36   5/21/2013
Issued to placement agents in August 2009     65     $ 1.50   8/21/2014
TorreyPines warrants assumed in 2009 Merger     8     $ 80.86 * 6/11/2013-9/26/2015
Issued to registered direct investors in Dec. 2009     631     $ 2.45   12/22/2014
Issued to private placement investors in Aug. 2010     3,095     $ 3.075   8/12/2015
Issued to placement agent in Aug. 2010     98     $ 3.075   8/12/2015
                   
Total warrants outstanding     4,563     $ 3.03 *  
                   
Schedule of assumptions used in fair value of warrrants
                      August 2010 private placement  
December 2009 equity financing     Investors and placement agent
      August 31,           August 31,  
  December 31, 2012   2012   2011     December 31, 2012   2012   2011  
Fair value ($ millions) $ 2.6   $ 2.9   $ 5.9     $ 13.8   $ 14.4   $ 17.7  
Black-Scholes inputs:                                      
  Stock price $ 5.85   $ 4.97   $ 4.73     $ 5.85   $ 4.97   $ 4.73  
  Exercise price $ 2.45   $ 2.45   $ 2.45     $ 3.075   $ 3.075   $ 3.075  
  Risk free interest rate   0.25 %   0.22 %   0.38 %     0.31 %   0.3 %   0.7 %
  Volatility   100 %   125 %   116 %     112 %   125 %   116 %
  Expected term (years)   2.00     2.25     3.25       2.5     3     4  
  Dividend   0     0     0       0     0     0