X0508 4 2023-09-15 0 0001070494 ACADIA PHARMACEUTICALS INC ACAD 0001816160 Kihara James C/O ACADIA PHARMACEUTICALS, INC. 12830 EL CAMINO REAL, SUITE 400 SAN DIEGO CA 92130 0 1 0 0 Principal Accounting Officer 1 Common Stock 2023-09-15 4 S 0 2000 25.88 D 10778 D The sales reported on this Form 4 were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 15, 2023. Includes an aggregate of 3,611 shares acquired by the Reporting Person under the Issuer's 2004 Employee Stock Purchase Plan on November 13, 2020, May 14, 2021, November 15, 2021, May 13, 2022, November 15, 2022 and May 15, 2023. Includes 23 shares purchased by the Reporting Person in open market transaction on November 21, 2020, with a purchase price of $43.01 per share. /s/ Austin D. Kim, Attorney-in-Fact 2023-09-19