X0306 4 2022-04-05 0 0001070494 ACADIA PHARMACEUTICALS INC ACAD 0001432545 Stankovic Srdjan R. C/O ACADIA PHARMACEUTICALS INC. 12830 EL CAMINO REAL, SUITE 400 SAN DIEGO CA 92130 0 1 0 0 President Stock Options (Right to Buy) 25.75 2022-04-05 4 A 0 124138 0.00 A 2032-04-05 Common Stock 124138 124138 D Restricted Stock Units 2022-04-05 4 A 0 36174 0.00 A Common Stock 36174 36174 D Restricted Stock Units 2022-04-05 4 A 0 144695 0.00 A Common Stock 144695 144695 D 25% of the shares subject to the Stock Option will vest and become exercisable on April 5, 2023. The remaining shares vest and become exercisable in 36 equal monthly installments thereafter. Each restricted stock unit represents a contingent right to receive one share of ACADIA common stock. The restricted stock units vest in four equal annual installments beginning April 5, 2023. Subject to accelerated vesting in certain circumstances, the restricted stock units vest as follows: 37.5% of the shares vest 18 months from the grant date; 12.5% of the shares vest on the second anniversary of the grant date; and 25% of the shares vest on each of the third and fourth anniversaries of the grant date. /s/ Austin D. Kim, Attorney-in-Fact 2022-04-07