144 0001579003 XXXXXXXX LIVE 0001070081 PTC THERAPEUTICS, INC. 001-35969 500 WARREN CORPORATE CENTER DRIVE WARREN NJ 07059 9082227000 Jacobson Allan Steven Director Common Fidelity Brokerage Services LLC

900 Salem Street Smithfield RI 02917

12000 780000.00 79438094 10/03/2025 NASDAQ Common 10/03/2025 Option Granted - 01/04/2016 Issuer N 12000 10/03/2025 Cash N Allan Jacobson

500 Warren Corporate Center Drive Warren NJ 07059

Common 08/28/2025 1667 83601.72 10/03/2025 03/12/2025 /s/ Jennifer Ruchti, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Allan Jacobson