X0303 4 2010-08-05 0 0001069530 PAIN THERAPEUTICS INC PTIE 0001133806 BARBIER REMI 1 1 1 0 CEO & Chairman of the Board Common Stock 2010-08-05 2010-08-05 4 S 0 3505 5.599 D 6045551 D Common Stock 2010-08-06 2010-08-06 4 S 0 9496 5.533 D 6036055 D Common Stock 2010-08-09 2010-08-09 4 S 0 6468 5.811 D 6029587 D This sale is made pursuant to a plan intended to comply with rule 10b5-1(c). 3,505 shares of common stock were sold in twelve (12) lots at prices ranging from $5.52 to $5.65 per share. This sale is made pursuant to a plan intended to comply with rule 10b5-1(c). 9,496 shares of common stock were sold in thirty (30) lots at prices ranging from $5.38 to $5.68 per share. This sale is made pursuant to a plan intended to comply with rule 10b5-1(c). 6,468 shares of common stock were sold in nineteen (19) lots at prices ranging from $5.62 to $5.88 per share. /s/Remi Barbier 2010-08-10