<SEC-DOCUMENT>0001654954-16-003104-index.html : 20161130
<SEC-HEADER>0001654954-16-003104.hdr.sgml : 20161130
<ACCEPTANCE-DATETIME>20161026163105
<PRIVATE-TO-PUBLIC>
ACCESSION NUMBER:		0001654954-16-003104
CONFORMED SUBMISSION TYPE:	CORRESP
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20161026

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opexa Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001069308
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				760333165
		STATE OF INCORPORATION:			TX
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		CORRESP

	BUSINESS ADDRESS:	
		STREET 1:		2635 TECHNOLOGY FOREST BLVD.
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381
		BUSINESS PHONE:		(281) 272-9331

	MAIL ADDRESS:	
		STREET 1:		2635 TECHNOLOGY FOREST BLVD.
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PharmaFrontiers Corp.
		DATE OF NAME CHANGE:	20051011

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PHARMAFRONTIERS CORP
		DATE OF NAME CHANGE:	20040816

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SPORTAN UNITED INDUSTRIES INC
		DATE OF NAME CHANGE:	19990305
</SEC-HEADER>
<DOCUMENT>
<TYPE>CORRESP
<SEQUENCE>1
<FILENAME>filename1.htm
<TEXT>
Document 1 - file: filename1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>opxa_corresp000.jpg
<DESCRIPTION>IMAGE
<TEXT>
Document 2 - file: opxa_corresp000.jpg

</DOCUMENT>
</SEC-DOCUMENT>