Stockholders' (Deficit) Equity - Additional Information (Details) - USD ($)							3 Months Ended		12 Months Ended
	Apr. 30, 2020	Mar. 18, 2020	Sep. 18, 2019	Nov. 09, 2018	May 14, 2018	Sep. 19, 2017	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Feb. 18, 2022	Jan. 01, 2022	Jan. 01, 2021
Stockholders Equity [Line Items]
Proceeds from issuance of common stock, net of issuance costs								$ 3,139,047
Number of share outstanding							2,796,100		1,954,975
Awards granted under the plan							853,000
Unrecognized compensation expense							$ 3,700,000
Share based compensation arrangement by share based payment award, Weighted average period							3 years 2 months 12 days
Weighted average grant date fair value of options granted							$ 1.99	$ 2.89
Fair value of options vested							$ 1,200,000	$ 800,000
2018 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of common stock authorized for issuance					500,000						572,410	529,325
Share-based compensation arrangement by share-based payment award, description							In addition, the number of shares authorized for issuance under the 2018 Plan is automatically increased (the “evergreen provision”) on the first day of each fiscal year beginning on January 1, 2019, and ending on (and including) January 1, 2028, in an amount equal to the lesser of (i) 4% of the outstanding shares of common stock on the last day of the immediately preceding fiscal year, or (ii) another amount (including zero) determined by the Company’s Board of Directors. On January 1, 2022 and 2021, 572,410 and 529,325 additional shares, respectively, were authorized according to the evergreen provision. On February18, 2022, the Company’s Board of Directors amended and restated the 2018 Plan to add a provision permitting the grant of inducement awards under Nasdaq Marketplace Rule 5635(c)(4) to eligible recipients and initially reserved 200,000 shares of the Company’s common stock for issuance pursuant to inducement awards granted under the 2018 Plan. Any shares subject to awards granted under the 2018 Plan that are forfeited or terminated before being exercised or settled, or are not delivered to the participant because such award is settled in cash, will again become available for issuance under the 2018 Plan. Shares withheld to satisfy the grant, exercise price or tax withholding obligation related to an award will again become available for issuance under the 2018 Plan.
Share-based compensation arrangement by share-based payment award, expiration date							Jan. 01, 2028
Share-based compensation arrangement by share-based payment award, percentage of outstanding our common stock							4.00%
Grant of inducement awards and reserved, shares										200,000
Options contractual term					10 years
Available for the grant of future awards							388,063
2018 Stock Incentive Plan | Executive Officers and Employees
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, stock options vesting period					4 years
2018 Stock Incentive Plan | Executive Officers and Employees | One-year Anniversary of the Grant Date
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage					25.00%
Awards granted under the plan							0	0	0
2018 Stock Incentive Plan | Executive Officers and Employees | Quarterly over Remaining Three Years
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage					75.00%
2018 Stock Incentive Plan | Executive Officers and Employees | January 1, 2021
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage			50.00%
2018 Stock Incentive Plan | Executive Officers and Employees | January 1, 2022
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, Vesting percentage			50.00%
2018 Stock Incentive Plan | Board of Directors
Stockholders Equity [Line Items]
Share-based compensation arrangement by share-based payment award, stock options vesting period					12 months
2013 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of common stock authorized for issuance						165,000
Options contractual term						10 years
Awards granted under the plan							0
2010 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of common stock authorized for issuance						470,170
Options contractual term						10 years
Awards granted under the plan							0
Lincoln Park
Stockholders Equity [Line Items]
Issuance of common stock, net of issuance costs, shares							0	200,000
Issuance of common stock, price per share								$ 2.47
Proceeds from issuance of common stock gross								$ 500,000
Proceeds from issuance of common stock, net of issuance costs								$ 500,000
Remaining obligation							$ 12,100,000
Number of shares, company may sell on any single business day	50,000
Maximum amount of Common stock at time of sale, per regular purchase	$ 1,000,000.0
Maximum percentage of shares may be issued or sold based on outstanding shares immediately prior to execution of agreement	19.99%
Issuance of common stock for commitment fee, shares	148,148
Fair value of the commitment fee shares, recorded to general and administrative expense along with other costs incurred	$ 400,000
Weighted Average | Lincoln Park
Stockholders Equity [Line Items]
Issuance of common stock, price per share								$ 2.47
Maximum | 2010 and 2013 Stock Incentive Plan
Stockholders Equity [Line Items]
Number of share outstanding					635,170
Maximum | Lincoln Park
Stockholders Equity [Line Items]
Shares value might be issued under agreement	$ 15,000,000.0
Number of shares, company may sell on any single business day	100,000
Beneficially ownership percentage	9.99%
Minimum [Member] | Lincoln Park
Stockholders Equity [Line Items]
Threshold price per share for issuance of shares under agreement	$ 2.1668
At-the-Market Facility
Stockholders Equity [Line Items]
Issuance of common stock, net of issuance costs, shares							0	877,107
Proceeds from issuance of common stock gross								$ 2,800,000
Common stock offering costs								200,000
Proceeds from issuance of common stock, net of issuance costs								$ 2,600,000
Amount remained available under facility							$ 40,000,000.0
At-the-Market Facility | Weighted Average
Stockholders Equity [Line Items]
Issuance of common stock, price per share								$ 3.1692
At-the-Market Facility | Maximum
Stockholders Equity [Line Items]
Aggregate offering price of common stock		$ 50,000,000.0		$ 50,000,000.0