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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Line Items]    
Provision for income taxes $ 0 $ 0
Net operating loss carryforwards 12,059,019 11,979,869
Research and development and orphan drug credits $ 8,700,000  
Net operating loss carryforwards term 20 years  
Net operating loss carryforwards expiration beginning year 2022  
Uncertain tax positions, accruals $ 0 0
Accruals for interest or penalties related to income tax matters 0 $ 0
U.S. Federal and State    
Income Tax Disclosure [Line Items]    
Net operating loss carryforwards 51,100,000  
State    
Income Tax Disclosure [Line Items]    
Net operating loss carryforwards 1,700,000  
Research and development and orphan drug credits $ 100,000