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Commitments and Contingencies - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Mar. 19, 2021
USD ($)
Jan. 25, 2021
USD ($)
Jan. 21, 2021
USD ($)
Jun. 05, 2020
Apr. 11, 2020
USD ($)
Sep. 27, 2017
USD ($)
Sep. 30, 2018
Patent
Aug. 31, 2016
Jun. 30, 2021
USD ($)
Jun. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Commitments And Contingencies [Line Items]                      
Reimbursement payment $ 14,000,000.0                    
Minimum percentage of loan proceeds used to cover payroll costs eligible for loan forgiven       60.00% 75.00%            
Gain on extinguishment of debt                   $ 568,909  
Other current assets                 $ 9,395,172 9,395,172  
Pending Litigation | Piper Sandler & Co.                      
Commitments And Contingencies [Line Items]                      
Loss contingency payable fees           $ 1,100,000          
Loss contingency closing date           Sep. 19, 2017          
Financing aggregate consideration           $ 15,700,000          
Reimbursement expenses           $ 100,000          
Pending Litigation | The Securities Class Action                      
Commitments And Contingencies [Line Items]                      
Proposed settlement as a loss in accrued expenses                 8,400,000 8,400,000  
Pending Litigation | Stockholders Derivative Action                      
Commitments And Contingencies [Line Items]                      
Payment of settlement plus legal fees and costs in excess of retention (deductible) amount     $ 500,000                
Other current assets                 1,000,000.0 $ 1,000,000.0  
PPP Loan                      
Commitments And Contingencies [Line Items]                      
Debt instrument, description                   On June 5, 2020, the Payroll Protection Flexibility Act of 2020 was signed into law, adjusting certain terms of the loans issued under the PPP, including extending the initial deferral period from six to up to ten months, reducing from 75% to 60% the portion of loan proceeds required to be used to cover payroll costs, and allowing borrowers to elect a 24-week rather than an eight-week period related to employment and compensation provisions.  
Gain on extinguishment of debt                 600,000    
PPP Loan | Other Current Liabilities                      
Commitments And Contingencies [Line Items]                      
CARES act of 2020 aid loan amount                     $ 400,000
PPP Loan | Other Non-current Liabilities                      
Commitments And Contingencies [Line Items]                      
CARES act of 2020 aid loan amount                     $ 200,000
PPP Loan | JPMorgan Chase Bank, N.A                      
Commitments And Contingencies [Line Items]                      
CARES act of 2020 aid loan amount         $ 600,000            
Promissory Note | JPMorgan Chase Bank, N.A                      
Commitments And Contingencies [Line Items]                      
Debt instrument, term         2 years            
Debt instrument, interest rate         1.00%            
Assistance Publique - Hopitaux de Paris ("AP-HP") | License Agreement                      
Commitments And Contingencies [Line Items]                      
Agreement entered date             2018-09        
Number of patent applications | Patent             3        
Assistance Publique - Hopitaux de Paris ("AP-HP") | Private Acer | License Agreement                      
Commitments And Contingencies [Line Items]                      
Agreement entered date               2016-08      
Relief | Collaboration Agreement                      
Commitments And Contingencies [Line Items]                      
Upfront non-refundable payment received   $ 1,000,000.0                  
Cash payment received 10,000,000.0 10,000,000.0                  
Reimbursement payment 14,000,000.0 14,000,000.0                  
Repayment of outstanding balance of prior loan and interest 4,000,000.0 4,000,000.0                  
Development and commercial launch costs $ 20,000,000.0                    
Guarantee for substantive review food and drug application   $ 0                  
Net profit split ratio based on territory 60.00% 60.00%                  
Percentage of royalty revenue received   15.00%                  
Milestone payment to be received $ 6,000,000.0 $ 6,000,000.0                  
Promissory note cancellation amount   4,000,000.0                  
Relief | Collaboration Agreement | First Development Payment                      
Commitments And Contingencies [Line Items]                      
Cash payment received                 10,000,000.0    
Development payments subject new drug application                 $ 10,000,000.0    
Relief | Collaboration Agreement | Second Development Payment                      
Commitments And Contingencies [Line Items]                      
Development payments subject new drug application $ 10,000,000.0 10,000,000.0               $ 10,000,000.0  
Relief | Collaboration Agreement | Maximum                      
Commitments And Contingencies [Line Items]                      
Development and commercial launch costs   $ 20,000,000.0                  
Relief | Collaboration Agreement | Secured Loan                      
Commitments And Contingencies [Line Items]                      
Debt instrument, term   12 months                  
Debt instrument, principal amount   $ 4,000,000.0                  
Debt instrument, interest rate   6.00%