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Stockholders' Equity - Additional Information (Details) - USD ($)
3 Months Ended
Jul. 24, 2020
Apr. 30, 2020
Mar. 18, 2020
Sep. 18, 2019
Nov. 09, 2018
May 14, 2018
Sep. 19, 2017
Mar. 31, 2021
Jan. 01, 2021
Dec. 31, 2020
Jan. 01, 2020
Stockholders Equity [Line Items]                      
Proceeds from issuance of common stock, net of issuance costs               $ 3,139,047      
Number of share outstanding               1,706,475   1,240,354  
Awards granted under the plan               485,000      
Unrecognized compensation expense               $ 3,700,000      
Share based compensation arrangement by share based payment award, Average remaining vesting period               2 years 4 months 24 days      
Weighted average grant date fair value of options granted               $ 2.89      
2018 Stock Incentive Plan                      
Stockholders Equity [Line Items]                      
Number of common stock authorized for issuance           500,000     529,325   403,807
Share-based compensation arrangement by share-based payment award, description               In addition, the number of shares authorized for issuance under the 2018 Plan is automatically increased (the “evergreen provision”) on the first day of each fiscal year beginning on January 1, 2019, and ending on (and including) January 1, 2028, in an amount equal to the lesser of (i) 4% of the outstanding shares of common stock on the last day of the immediately preceding fiscal year, or (ii) another amount (including zero) determined by the Company’s Board of Directors. Any shares subject to awards granted under the 2018 Plan that are forfeited or terminated before being exercised or settled, or are not delivered to the participant because such award is settled in cash, will again become available for issuance under the 2018 Plan. Shares withheld to satisfy the grant, exercise price or tax withholding obligation related to an award will again become available for issuance under the 2018 Plan.      
Share-based compensation arrangement by share-based payment award, expiration date               Jan. 01, 2028      
Share-based compensation arrangement by share-based payment award, percentage of outstanding our common stock               4.00%      
Options contractual term           10 years          
Available for the grant of future awards               705,278      
2013 Stock Incentive Plan                      
Stockholders Equity [Line Items]                      
Number of common stock authorized for issuance             165,000        
Options contractual term             10 years        
Awards granted under the plan               0      
2010 Stock Incentive Plan                      
Stockholders Equity [Line Items]                      
Number of common stock authorized for issuance             470,170        
Options contractual term             10 years        
Awards granted under the plan               0      
Lincoln Park                      
Stockholders Equity [Line Items]                      
Issuance of common stock               200,000      
Issuance of common stock, price per share               $ 2.47      
Proceeds from issuance of common stock gross               $ 500,000      
Proceeds from issuance of common stock, net of issuance costs               $ 500,000      
Number of shares, company may sell on any single business day   50,000                  
Maximum amount of Common stock at time of sale, per regular purchase   $ 1,000,000                  
Maximum percentage of shares may be issued or sold based on outstanding shares immediately prior to execution of agreement   19.99%                  
Issuance of common stock for commitment fee, shares   148,148                  
Fair value of the commitment fee shares, recorded to general and administrative expense along with other costs   $ 400,000                  
Cost, Product and Service [Extensible List]   General and Administrative                  
Executive Officers and Employees | 2018 Stock Incentive Plan                      
Stockholders Equity [Line Items]                      
Share-based compensation arrangement by share-based payment award, stock options vesting period           4 years          
Executive Officers and Employees | 2018 Stock Incentive Plan | One-year Anniversary of the Grant Date                      
Stockholders Equity [Line Items]                      
Share-based compensation arrangement by share-based payment award, Vesting percentage           25.00%          
Executive Officers and Employees | 2018 Stock Incentive Plan | Quarterly over Remaining Three Years                      
Stockholders Equity [Line Items]                      
Share-based compensation arrangement by share-based payment award, Vesting percentage           75.00%          
Executive Officers and Employees | 2018 Stock Incentive Plan | January 1, 2021                      
Stockholders Equity [Line Items]                      
Share-based compensation arrangement by share-based payment award, Vesting percentage       50.00%              
Executive Officers and Employees | 2018 Stock Incentive Plan | January 1, 2022                      
Stockholders Equity [Line Items]                      
Share-based compensation arrangement by share-based payment award, Vesting percentage       50.00%              
Weighted Average | Lincoln Park                      
Stockholders Equity [Line Items]                      
Issuance of common stock, price per share               $ 2.47      
Maximum | 2010 and 2013 Stock Incentive Plan                      
Stockholders Equity [Line Items]                      
Number of share outstanding           635,170          
Maximum | Lincoln Park                      
Stockholders Equity [Line Items]                      
Shares value might be issued under agreement   $ 15,000,000                  
Number of shares, company may sell on any single business day   100,000                  
Beneficially ownership percentage   9.99%                  
Minimum | Lincoln Park                      
Stockholders Equity [Line Items]                      
Threshold price per share for issuance of shares under agreement   $ 2.1668                  
At-the-Market Facility                      
Stockholders Equity [Line Items]                      
Issuance of common stock               877,107      
Proceeds from issuance of common stock gross               $ 2,800,000      
Common stock offering costs               200,000      
Proceeds from issuance of common stock, net of issuance costs               $ 2,600,000      
At-the-Market Facility | Weighted Average                      
Stockholders Equity [Line Items]                      
Issuance of common stock, price per share               $ 3.1692      
At-the-Market Facility | Maximum                      
Stockholders Equity [Line Items]                      
Aggregate offering price of common stock     $ 50,000,000   $ 50,000,000            
Private Placement | Directors, Officers and Employees                      
Stockholders Equity [Line Items]                      
Issuance of common stock 244,998                    
Issuance of common stock, price per share $ 3.50                    
Proceeds from issuance of common stock, net of issuance costs $ 900,000