Nature of Operations and Basis of Presentation - Additional Information (Details) - USD ($)							3 Months Ended
	Mar. 19, 2021	Jan. 25, 2021	Jul. 24, 2020	Apr. 30, 2020	Mar. 18, 2020	Nov. 09, 2018	Mar. 31, 2021	Mar. 31, 2020	Dec. 31, 2020
Organization Consolidation and Presentation of Financial Statement [Line Items]
Accumulated deficit							$ 100,649,133		$ 99,135,961
Cash and cash equivalents							15,900,297		5,761,568
Net cash used in operating activities							3,005,004	$ (5,070,380)
Proceeds from issuance of common stock, net of issuance costs							3,139,047
Reimbursement payment	$ 14,000,000
Development payments	10,000,000
Current liabilities							34,035,435		$ 6,145,546
Deferred collaboration funding							20,715,764
Liability related to securities class action and stockholder derivative actions settlements and legal costs							$ 9,800,000
Lincoln Park
Organization Consolidation and Presentation of Financial Statement [Line Items]
Issuance of common stock							200,000
Issuance of common stock, price per share							$ 2.47
Proceeds from issuance of common stock gross							$ 500,000
Proceeds from issuance of common stock, net of issuance costs							500,000
Number of shares, company may sell on any single business day				50,000
Maximum amount of Common stock at time of sale, per regular purchase				$ 1,000,000
Issuance of common stock for commitment fee, shares				148,148
Fair value of the commitment fee shares, recorded to general and administrative expense along with other costs				$ 400,000
Cost, Product and Service [Extensible List]				General and Administrative
Stock to be issued value on certain limitation and condition				$ 15,000,000
Collaboration Agreement | Relief
Organization Consolidation and Presentation of Financial Statement [Line Items]
Upfront non-refundable payment received		$ 1,000,000
Reimbursement payment	14,000,000	14,000,000
Development payments subject new drug application		10,000,000					$ 10,000,000
Milestone payment to be received	$ 6,000,000	6,000,000
Weighted Average | Lincoln Park
Organization Consolidation and Presentation of Financial Statement [Line Items]
Issuance of common stock, price per share							$ 2.47
Maximum | Lincoln Park
Organization Consolidation and Presentation of Financial Statement [Line Items]
Shares value might be issued under agreement				$ 15,000,000
Number of shares, company may sell on any single business day				100,000
Maximum | Collaboration Agreement | Relief
Organization Consolidation and Presentation of Financial Statement [Line Items]
Development payments		$ 20,000,000					$ 20,000,000
At-the-Market Facility
Organization Consolidation and Presentation of Financial Statement [Line Items]
Issuance of common stock							877,107
Proceeds from issuance of common stock gross							$ 2,800,000
Common stock offering costs							200,000
Proceeds from issuance of common stock, net of issuance costs							$ 2,600,000
At-the-Market Facility | Weighted Average
Organization Consolidation and Presentation of Financial Statement [Line Items]
Issuance of common stock, price per share							$ 3.1692
At-the-Market Facility | Maximum
Organization Consolidation and Presentation of Financial Statement [Line Items]
Aggregate offering price of common stock					$ 50,000,000	$ 50,000,000
Private Placement | Directors, Officers and Employees
Organization Consolidation and Presentation of Financial Statement [Line Items]
Issuance of common stock			244,998
Issuance of common stock, price per share			$ 3.50
Proceeds from issuance of common stock, net of issuance costs			$ 900,000