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Nature of Operations and Basis of Presentation - Additional Information (Details)
1 Months Ended 2 Months Ended 7 Months Ended 12 Months Ended
Jan. 25, 2021
USD ($)
Jul. 24, 2020
USD ($)
$ / shares
shares
Apr. 30, 2020
USD ($)
shares
Mar. 18, 2020
USD ($)
Nov. 09, 2018
USD ($)
Jun. 30, 2019
Employee
Mar. 01, 2021
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Dec. 31, 2019
USD ($)
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Restructuring implemented date                 Jun. 30, 2019  
Corporate restructuring, reduction of full-time workforce percentage           60.00%        
Corporate restructuring, reduction of full-time workforce employees | Employee           48        
Restructuring completion date                 Dec. 31, 2019  
Accumulated deficit               $ 99,135,961 $ 99,135,961 $ 76,250,512
Cash and cash equivalents               5,761,568 5,761,568 12,077,640
Net cash used in operating activities                 17,027,415 29,506,949
Proceeds from issuance of common stock, net of issuance costs                 10,159,766  
Current liabilities               $ 6,145,546 6,145,546 $ 2,768,913
Issuance of common stock, net of issuance costs                 $ 10,159,766  
Lincoln Park                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, net of issuance costs, shares | shares                 900,000  
Issuance of common stock, price per share | $ / shares               $ 2.64 $ 2.64  
Proceeds from issuance of common stock gross                 $ 2,400,000  
Common stock offering costs                 200,000  
Proceeds from issuance of common stock, net of issuance costs                 2,200,000  
Shares value might be issued under agreement     $ 15,000,000              
Number of shares, company may sell on any single business day | shares     50,000              
Maximum amount of Common stock at time of sale, per regular purchase     $ 1,000,000              
Issuance of common stock for commitment fee, shares | shares     148,148              
Fair value of the commitment fee shares, recorded to general and administrative expense along with other costs     $ 400,000              
Cost, Product and Service [Extensible List]     us-gaap:GeneralAndAdministrativeExpenseMember              
Issuance of common stock, net of issuance costs     $ 15,000,000              
Lincoln Park | Subsequent Event                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, net of issuance costs, shares | shares             200,000      
Issuance of common stock, price per share | $ / shares             $ 2.47      
Proceeds from issuance of common stock gross             $ 500,000      
Proposed Collaboration and License Agreement | Relief Therapeutics Holding AG                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Potential loan offset amount               $ 4,000,000 $ 4,000,000  
Debt instrument, maturity date                 Jan. 25, 2022  
Proposed Collaboration and License Agreement | Relief Therapeutics Holding AG | Secured Loan                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Debt instrument, term                 12 months  
Debt instrument, principal amount               $ 4,000,000 $ 4,000,000  
Proposed Collaboration and License Agreement | Subsequent Event | Relief Therapeutics Holding AG                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Upfront non-refundable payment received $ 1,000,000                  
Potential cash receivable 14,000,000                  
Potential offset to cash receivable $ 4,000,000                  
Proposed Collaboration and License Agreement | Subsequent Event | Secured Loan | Relief Therapeutics Holding AG                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Debt instrument, term 12 months                  
Debt instrument, principal amount $ 4,000,000                  
Debt instrument, interest rate 6.00%                  
Weighted Average | Lincoln Park                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, price per share | $ / shares               $ 2.64 $ 2.64  
Maximum | Lincoln Park                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Shares value might be issued under agreement     $ 15,000,000              
Number of shares, company may sell on any single business day | shares     100,000              
At-the-Market Facility                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, net of issuance costs, shares | shares               1,838,957    
Proceeds from issuance of common stock gross               $ 7,200,000    
Common stock offering costs               300,000    
Proceeds from issuance of common stock, net of issuance costs               $ 6,900,000    
At-the-Market Facility | Subsequent Event                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, net of issuance costs, shares | shares             877,107      
Proceeds from issuance of common stock gross             $ 2,800,000      
At-the-Market Facility | Weighted Average                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, price per share | $ / shares               $ 3.9228 $ 3.9228  
At-the-Market Facility | Weighted Average | Subsequent Event                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, price per share | $ / shares             $ 3.17      
At-the-Market Facility | Maximum                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Aggregate offering price of common stock       $ 50,000,000 $ 50,000,000          
Private Placement | Directors, Officers and Employees                    
Organization Consolidation and Presentation of Financial Statement [Line Items]                    
Issuance of common stock, net of issuance costs, shares | shares   244,998                
Issuance of common stock, price per share | $ / shares   $ 3.50                
Proceeds from issuance of common stock, net of issuance costs   $ 900,000