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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Line Items]    
Provision for income taxes $ 0 $ 0
Net operating loss carryforwards 3,604,179 $ 1,843,000
Research and development and orphan drug credits $ 6,300,000  
Net operating loss carryforwards term 20 years  
Net operating loss carryforwards expiration beginning year 2022  
Corporate federal income tax rate 21.00% 34.00%
Reduction in deferred tax assets   $ 8,200,000
State    
Income Tax Disclosure [Line Items]    
Net operating loss carryforwards $ 15,900,000