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Nature of Operations and Basis of Presentation - Additional Information (Details)
12 Months Ended
Sep. 19, 2017
$ / shares
shares
Sep. 18, 2017
USD ($)
$ / shares
Dec. 31, 2018
USD ($)
$ / shares
shares
Dec. 31, 2017
USD ($)
$ / shares
shares
May 15, 2018
$ / shares
May 14, 2018
$ / shares
Organization Consolidation and Presentation of Financial Statement [Line Items]            
Common stock, shares outstanding | shares 6,500,000   10,087,363 7,497,433    
Aggregate common stock issued and sold prior to merger | $     $ 42,622,700 $ 21,506,842    
Shares issued price per share $ 9.47          
Preferred stock, no par value       $ 0   $ 0
Preferred stock, par value     $ 0.0001      
Common stock, par value     $ 0.0001 $ 0.01   $ 0.01
Private Acer            
Organization Consolidation and Presentation of Financial Statement [Line Items]            
Percentage of outstanding common stock owned by acquirer's shareholders 89.00%          
Percentage of outstanding common stock owned by registrant's shareholders 11.00%          
Private Acer            
Organization Consolidation and Presentation of Financial Statement [Line Items]            
Shares issued in exchange of common stock upon merger | shares 1          
Aggregate common stock issued and sold prior to merger | $   $ 15,700,000        
Shares issued price per share   $ 9.47        
Private Acer | Convertible Promissory Notes            
Organization Consolidation and Presentation of Financial Statement [Line Items]            
Debt conversion, outstanding principal and accrued interest | $   $ 5,700,000        
Merger of Private Acer with Opexa Merger Sub Incorporation            
Organization Consolidation and Presentation of Financial Statement [Line Items]            
Business combination date of completion Sep. 19, 2017          
Business combination date of agreement Jun. 30, 2017          
Reverse stock split ratio 0.09656678989          
Delaware Reincorporation and Subsidiary Merger            
Organization Consolidation and Presentation of Financial Statement [Line Items]            
Merger incorporation description     On May 15, 2018, the Company changed its state of incorporation from the State of Texas to the State of Delaware pursuant to a plan of conversion, dated May 15, 2018. As a result of this reincorporation, the par value of the Company’s preferred stock was changed from no par value to $0.0001 and the par value of the Company’s common stock was reduced to $0.0001 from $0.01.      
Date Of Reincorporation     May 15, 2018      
Preferred stock, par value         $ 0.0001  
Common stock, par value         $ 0.0001