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Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2018

Summary of Option Activity under 2013 Plan and 2010 Plan

A summary of option activity under the 2018 Plan, 2013 Plan and 2010 Plan for the nine months ended September 30, 2018, is as follows:

	Number of Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (in millions)
Options outstanding at December 31, 2017		463,600	$	11.23	9.5
Granted		287,500	$	21.13
Options outstanding at September 30, 2018		751,100	$	15.02	9.0	$	11.9
Options exercisable at September 30, 2018		170,947	$	4.32	7.7	$	4.5

Summary of Stock-Based Compensation Expense

The amount of stock-based compensation expense recorded to research and development and to general and administrative is detailed in table below:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2018		2017		2018		2017
Stock-based compensation
Research and development	$	179,930	$	99,847	$	515,584	$	118,233
General and administrative		172,786		6,151		415,933		18,384
	$	352,716	$	105,998	$	931,517	$	136,617

Summary of Warrant Activity

A summary of warrant activity for the nine months ended September 30, 2018 is presented below:

	Number of Shares			Weighted Average Exercise Price		Weighted Average Remaining Contract Term (# years)		Intrinsic Value
Outstanding and exercisable at December 31, 2017		317,630		$	123.61	0.54			—
Canceled/forfeited		(306,656	)	$	135.58
Outstanding and exercisable at September 30, 2018		10,974		$	124.27		0.02		—

- Definition

Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable.

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