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Stockholders' Equity - Additional Information (Details) - USD ($)
3 Months Ended
Jan. 29, 2018
Jan. 23, 2018
Sep. 19, 2017
Mar. 31, 2018
Sep. 18, 2017
Stockholders Equity [Line Items]          
Unrecognized compensation expense       $ 2,900,000  
Share based compensation arrangement by share based payment award, Average remaining vesting period       3 years 6 months  
Weighted average grant date fair value of options granted       $ 10.00  
Series J Warrants          
Stockholders Equity [Line Items]          
Warants expired for aggregate share of common stock to purrchase   2,942      
Series K Warrants          
Stockholders Equity [Line Items]          
Warants expired for aggregate share of common stock to purrchase 2,262        
Research and Development          
Stockholders Equity [Line Items]          
Stock based compensation expense       $ 153,000  
General and Administrative          
Stockholders Equity [Line Items]          
Stock based compensation expense       $ 100,000  
2010 Stock Incentive Plan          
Stockholders Equity [Line Items]          
Number of common stock authorized for issuance     470,170   113,465
Options contractual term     10 years    
Available for the grant of future awards       97,072  
2010 Stock Incentive Plan | Executive Officers and Employees          
Stockholders Equity [Line Items]          
Share-based compensation arrangement by share-based payment award, stock options vesting period     4 years    
2010 Stock Incentive Plan | Executive Officers and Employees | One-year Anniversary of the Grant Date          
Stockholders Equity [Line Items]          
Share-based compensation arrangement by share-based payment award, Vesting percentage     25.00%    
2010 Stock Incentive Plan | Executive Officers and Employees | Quarterly over Remaining Three Years          
Stockholders Equity [Line Items]          
Share-based compensation arrangement by share-based payment award, Vesting percentage     75.00%    
2013 Stock Incentive Plan          
Stockholders Equity [Line Items]          
Number of common stock authorized for issuance     165,000    
Options contractual term     10 years