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Stockholders' Equity - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 27, 2017
Dec. 14, 2017
Sep. 19, 2017
Dec. 31, 2017
Dec. 31, 2016
Sep. 18, 2017
Stockholders Equity [Line Items]            
Conversion of convertible notes payable and accrued interest to common stock, value     $ 5,674,452 $ 5,674,452 $ 0  
Conversion of convertible notes payable and accrued interest to common stock, shares     599,201      
Issuance of common stock, net of issuance costs, shares     1,055,961      
Shares issued price per share     $ 9.47      
Proceeds from issuance of common stock     $ 10,000,000 21,506,842 $ 0  
Unrecognized compensation expense       $ 2,500,000    
Share based compensation arrangement by share based payment award, Average remaining vesting period       3 years 3 months 18 days    
Weighted average grant date fair value of options granted       $ 8.25 $ 1.32  
General and Administrative            
Stockholders Equity [Line Items]            
Stock based compensation expense       $ 111,000    
Research and Development            
Stockholders Equity [Line Items]            
Stock based compensation expense       $ 307,000    
2010 Stock Incentive Plan            
Stockholders Equity [Line Items]            
Number of common stock authorized for issuance     470,170     113,465
Options contractual term     10 years      
Number of underlying shares cancelled     22,061      
Available for the grant of future awards       159,572    
2010 Stock Incentive Plan | Executive Officers and Employees            
Stockholders Equity [Line Items]            
Share-based compensation arrangement by share-based payment award, stock options vesting period     4 years      
2010 Stock Incentive Plan | Executive Officers and Employees | One-year Anniversary of the Grant Date            
Stockholders Equity [Line Items]            
Share-based compensation arrangement by share-based payment award, Vesting percentage     25.00%      
2010 Stock Incentive Plan | Executive Officers and Employees | Quarterly over Remaining Three Years            
Stockholders Equity [Line Items]            
Share-based compensation arrangement by share-based payment award, Vesting percentage     75.00%      
2013 Stock Incentive Plan            
Stockholders Equity [Line Items]            
Number of common stock authorized for issuance     165,000      
Options contractual term     10 years      
Underwritten public offering and over-allotment option            
Stockholders Equity [Line Items]            
Issuance of common stock, net of issuance costs, shares 130,000 916,667        
Shares issued price per share $ 12.00 $ 12.00        
Proceeds from issuance of common stock $ 1,600,000 $ 11,000,000   $ 1,100,000    
Registrant            
Stockholders Equity [Line Items]            
Common stock held by existing shareholders     736,950      
Series A Convertible Redeemable Preferred Stock            
Stockholders Equity [Line Items]            
Number of preferred stock converted to common stock     638,416      
Series B Convertible Redeemable Preferred Stock            
Stockholders Equity [Line Items]            
Number of preferred stock converted to common stock     970,238