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Nature of Operations and Basis of Presentation - Additional Information (Details)
12 Months Ended
Sep. 19, 2017
$ / shares
shares
Sep. 18, 2017
USD ($)
$ / shares
Dec. 31, 2017
USD ($)
Patient
shares
Dec. 31, 2016
shares
Organization Consolidation and Presentation of Financial Statement [Line Items]        
Number of patients unapproved | Patient     7,000  
Common stock, shares outstanding | shares 6,500,000   7,497,433 2,450,000
Aggregate common stock issued and sold prior to merger     $ 21,506,842  
Shares issued price per share | $ / shares $ 9.47      
Private Acer        
Organization Consolidation and Presentation of Financial Statement [Line Items]        
Shares issued in exchange of common stock upon merger 1.00%      
Percentage of outstanding common stock owned by acquirer's shareholders 89.00%      
Percentage of outstanding common stock owned by registrant's shareholders 11.00%      
Aggregate common stock issued and sold prior to merger   $ 15,700,000    
Shares issued price per share | $ / shares   $ 9.47    
Private Acer | Convertible Promissory Notes        
Organization Consolidation and Presentation of Financial Statement [Line Items]        
Debt conversion, outstanding principal and accrued interest   $ 5,700,000    
Merger of Private Acer with Opexa Merger Sub Incorporation        
Organization Consolidation and Presentation of Financial Statement [Line Items]        
Business combination date of completion Sep. 19, 2017      
Business combination date of agreement Jun. 30, 2017      
Reverse stock split ratio 0.09656678989