Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
Revenue:
Option Revenue	$ 2,556,329	$ 1,271,895
Research and development	10,039,496	12,118,629
General and administrative	4,258,147	3,833,370
Depreciation and amortization	351,403	387,779
Loss on disposal of fixed assets	1,167	0
Operating loss	(12,093,884)	(15,067,883)
Interest income, net	5,911	13,473
Other income and expense, net	68,695	2,147
Net loss	$ (12,019,278)	$ (15,052,263)
Basic and diluted loss per share	$ (2.05)	$ (4.33)
Weighted average shares outstanding	5,854,438	3,477,628