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Consolidated Statements of Operations (USD $)
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Revenue:    
Option Revenue $ 377,453us-gaap_ContractsRevenue $ 348,837us-gaap_ContractsRevenue
Research and development 2,636,999us-gaap_ResearchAndDevelopmentExpense 2,811,139us-gaap_ResearchAndDevelopmentExpense
General and administrative 1,006,130us-gaap_GeneralAndAdministrativeExpense 1,102,880us-gaap_GeneralAndAdministrativeExpense
Depreciation and amortization 96,982us-gaap_DepreciationAndAmortization 95,586us-gaap_DepreciationAndAmortization
Operating loss (3,362,658)us-gaap_OperatingIncomeLoss (3,660,768)us-gaap_OperatingIncomeLoss
Interest income 1,478us-gaap_InvestmentIncomeInterest 5,194us-gaap_InvestmentIncomeInterest
Other income, net 10,300us-gaap_OtherNonoperatingIncomeExpense 0us-gaap_OtherNonoperatingIncomeExpense
Net loss $ (3,350,880)us-gaap_NetIncomeLoss $ (3,655,574)us-gaap_NetIncomeLoss
Basic and diluted loss per share $ (0.12)us-gaap_EarningsPerShareBasicAndDiluted $ (0.13)us-gaap_EarningsPerShareBasicAndDiluted
Weighted average shares outstanding - Basic and diluted 28,234,751us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted 27,584,615us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted