X0306 4 2015-04-08 0 0001069308 Opexa Therapeutics, Inc. OPXA 0001437911 Warma Neil K C/O OPEXA THERAPEUTICS, INC. 2635 TECHNOLOGY FOREST BLVD. THE WOODLANDS TX 77381 1 1 President and CEO Common Stock 2015-04-08 4 M 0 37247 A 144881 D Subscription Rights (Right to Buy) 0.55 2015-04-08 4 M 0 37247 0 D 2015-03-13 2015-04-08 See Footnote 37247 0 D Warrants (Right to Buy) 2015-04-08 4 M 0 37247 A 2015-04-08 2018-04-08 Common Stock 37247 37247 D The common stock and the warrants reported on this Form 4 were acquired pursuant to the exercise of subscription rights previously distributed by Opexa Therapeutics, Inc. (the ?Company?) to all holders of the Company?s common stock and to holders of certain of the Company?s outstanding warrants. The subscription rights entitled each recipient thereof to purchase units (?Units?), each Unit consisting of one share of the Company?s common stock and one warrant representing the right to purchase one share of the Company?s common stock. The purchase price for each Unit was $0.55. Each warrant entitles the holder to purchase one share of the Company?s common stock at an exercise price of (i) $0.50 per share from the date of issuance through June 30, 2016 and (ii) $1.50 per share from July 1, 2016 through the expiration date of the warrants. /s/ Neil Warma 2015-04-09