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Consolidated Statements of Cash Flows (USD $)
3 Months Ended 12 Months Ended 119 Months Ended 122 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2012
Mar. 31, 2013
Cash flows from operating activities            
Net loss $ (4,177,482) $ (2,373,999) $ (8,930,833) $ (5,968,448) $ (109,611,620) $ (113,789,102)
Adjustments to reconcile net loss to net cash used in operating activities            
Stock payable for acquired research and development         112,440 112,440
Stock issued for acquired research and development         26,286,589 26,286,589
Stock issued for services       87,028 2,061,743 2,061,743
Stock issued for debt in excess of principal         109,070 109,070
Amortization of discount on notes payable due to warrants and beneficial conversion feature 1,237,662   104,032   6,856,730 8,094,392
Gain on extinguishment of debt         (1,612,440) (1,612,440)
Depreciation 78,311 67,355 303,677 210,252 1,650,158 1,728,469
Amortization of debt financing costs 52,939   58,639   583,017 635,956
Option and warrant expense 411,187 205,420 690,726 489,914 16,265,933 16,677,120
Loss/(Gain) on derivative instruments     (552,978)   (1,941,826) (1,941,826)
Loss on disposal of fixed assets     3,097 9,686 513,345 513,345
Changes in:            
Deferred revenue 4,779,900         4,779,900
Other current assets (115,589) (880,983) (611,607) (39,248) (1,153,053) (1,268,642)
Accounts payable - third parties and related parties 418,562 1,022,532 (71,410) (13,028) (160,651) 257,911
Accrued expenses 457,240 (225,743) 83,018 234,923 605,238 1,062,478
Other assets (104,027)         (104,027)
Net cash provided by (used in) operating activities 3,038,703 (2,185,418) (8,923,639) (4,988,921) (59,435,327) (56,396,624)
Cash flows from investing activities            
Purchase of property & equipment (2,598) (245,841) (550,389) (296,949) (2,222,199) (2,224,797)
Restricted cash 500,000   (1,000,000)   (1,000,000) (500,000)
Net cash provided by (used in) investing activities 497,402 (245,841) (1,550,389) (296,949) (3,222,199) (2,724,797)
Cash flows from financing activities            
Common stock and warrants sold for cash, net of offering costs 3,623,738   381,309 8,618,157 49,453,797 53,077,535
Common stock repurchased and canceled         (325) (325)
Proceeds from exercise of warrants and options         1,248,588 1,248,588
Deferred financing and offering costs (17,511)   (509,492)   (509,492) (527,003)
Repayments on loan payable       (35,607) (311,222)  
Repayments on notes payable (450,000)         (761,222)
Net cash provided by financing activities 3,706,227   3,956,817 8,582,550 63,249,530 66,955,757
Net change in cash and cash equivalents 7,242,332 (2,431,259) (6,517,211) 3,296,680 592,004 7,834,336
Cash and cash equivalents at beginning of period 592,004 7,109,215 7,109,215 3,812,535    
Cash and cash equivalents at end of period 7,834,336 4,677,956 592,004 7,109,215 592,004 7,834,336
Cash paid for:            
Income tax                  
Interest 18,647 487 1,946 3,135 155,109 173,756
NON-CASH TRANSACTIONS            
Issuance of common stock to Sportan shareholders         147,733 147,733
Issuance of common stock for accrued interest     185,683   789,287 789,287
Issuance of warrants to placement agent         37,453 37,453
Conversion of notes payable to common stock 1,000,000       7,709,980 8,709,980
Conversion of accrued liabilities to common stock         197,176 197,176
Conversion of accounts payable to note payable         93,364 93,364
Discount on convertible notes relating to:            
Warrants 195,969   2,314,635   5,974,372 6,170,341
Beneficial conversion feature 141,829   1,497,634   3,303,153 3,444,982
Stock attached to notes         1,287,440 1,287,440
Fair value of derivative instrument         4,680,220 4,680,220
Derivative reclassified to equity     1,761,657   2,349,266 2,349,266
Unpaid additions to property and equipment   182,952 7,812 136,266 144,078  
Amortization of deferred offering costs to paid-in capital 45,450   47,339   47,339 92,789
Shares issued as deferred offering costs 1,234   149,131   149,131 150,365
Third Parties
           
Cash flows from financing activities            
Proceeds from convertible debt 550,000   3,455,000   12,738,184 13,288,184
Related Parties
           
Cash flows from financing activities            
Proceeds from convertible debt 100,000   630,000   630,000 730,000
Related Party
           
Cash flows from financing activities            
Repayments on notes payable $ (100,000)         $ (100,000)