Consolidated Statements of Changes in Stockholders' Equity (USD $)	Common Stock [Member]	Additional Paid In Capital [Member]	Accumulated Deficit	Total
Beginning Balance, Amount at Dec. 31, 2012	$ 62,494	$ 112,432,458	$ (109,611,620)	$ 2,883,332
Beginning Balance, Shares at Dec. 31, 2012	6,249,369
Conversion of convertible notes, Shares	2,079,960
Conversion of convertible notes, amount	20,799	4,254,254		4,275,053
Discount related to beneficial conversion feature		141,829		141,829
Discount on warrants attached to debt		195,969		195,969
Shares issued for initial commitment on Lincoln Park $1.5 million share purchase agreement, Shares	975
Shares issued for initial commitment on Lincoln Park $1.5 million share purchase agreement, Amount	10	1,224		1,234
Shares issued for cash, net of offering costs, Shares	19,013,952
Shares issued for cash, net of offering costs, Amount	190,140	28,157,960		28,348,100
Shares issued for accrued interest, Shares	123,231
Shares issued for accrued interest, Amount	1,232	187,311		188,543
Shares issued for restricted stock awards, Shares	78,571
Shares issued for restricted stock awards, amount	786	69,113		69,899
Warrant expense		219,553		219,553
Option expense		910,087		910,087
Net loss			(16,656,325)	(16,656,325)
Ending Balance, Amount at Dec. 31, 2013	275,461	146,569,758	(126,267,945)	20,577,274
Ending Balance, Shares at Dec. 31, 2013	27,546,058
Shares issued for cash, net of offering costs, Shares	518,412
Shares issued for cash, net of offering costs, Amount	5,184	642,991		648,175
Shares issued for services, Shares	1,703	304,400		306,103
Shares issued for services, Amount	170,281
Option expense		959,898		959,898
Net loss			(15,052,263)	(15,052,263)
Ending Balance, Amount at Dec. 31, 2014	$ 282,348	$ 148,477,047	$ (141,320,208)	$ 7,439,187
Ending Balance, Shares at Dec. 31, 2014	28,234,751