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Significant Contractual Service and Milestone Agreements - Additional Information (Detail) (Service agreement with Pharmaceutical Research Associates Inc, USD $)
1 Months Ended 12 Months Ended
Feb. 28, 2012
Dec. 31, 2013
Dec. 31, 2012
Service agreement with Pharmaceutical Research Associates Inc
     
Schedule Of Contractual Commitments [Line Items]      
Agreement initial term 4 years    
Agreements additional term after renewal in years 1 year    
Notice period before termination of agreement 60 days    
Total payment charged to expense   $ 1,582,380 $ 1,382,236