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Stock-Based Compensation - Additional Information (Detail) (USD $)
1 Months Ended 9 Months Ended
Feb. 11, 2013
Jan. 23, 2013
Jan. 29, 2013
Sep. 30, 2013
Jan. 31, 2013
Dec. 31, 2012
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Share based compensation, common stock shares issued and outstanding       1,094,854   824,620
Option expense recognized       $ 705,408    
Unamortized stock compensation expense       970,912    
Number of Shares, Granted       342,572    
Expected dividends       0    
Number of Shares, Forfeited and canceled       72,338    
Warrant term 4 years 5 years 5 years      
Warrants issued to purchase common stock   243,750 187,500   243,750  
Warrant exercise price $ 3.00 $ 1.24 $ 1.21      
Warrant redemption price per share   $ 0.01 $ 0.01      
Terms for warrant redeem   Opexa can redeem the warrants at $0.01 per share if the Company's common stock closes at or above $10.00 per share for 20 consecutive trading days. The warrants at $0.01 per underlying share of common stock if the common stock closes at or above $10.00 per share for 20 consecutive trading days.      
Number of common stock to be issued upon exercise of warrant 541,668   187,500      
Warrants Attached to Debt
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Discount rate   0.76%        
Expected life   5 years        
Expected volatility rate   191.00%        
Expected dividends   0        
Estimated fair value of warrants   195,969        
Warrants, Forfeited and canceled       1,482,892    
Common Stock Warrants issued to Release a Claim on Cash
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Discount rate     0.90%      
Expected life     5 years      
Expected volatility rate     191.00%      
Estimated fair value of warrants     219,553      
Employee Stock Option
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Stock option, term       10 years    
Employee Stock Option | Employee
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Stock option, term       10 years    
Number of Shares, Granted       125,000    
Weighted average exercise price, Granted       $ 2.34    
Vesting period       3 years    
Fair value of stock granted during period       285,226    
Discount rate       1.87%    
Expected life       5 years 3 months    
Expected volatility rate       194.00%    
Expected dividends       0    
Employee Stock Option | Employees
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Stock option, term       10 years    
Number of Shares, Granted       129,000    
Vesting period       3 years    
Fair value of stock granted during period       218,348    
Expected life       5 years 3 months    
Expected dividends       $ 0    
Employee Stock Option | Employees | Minimum
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Weighted average exercise price, Granted       $ 1.45    
Discount rate       1.73%    
Expected volatility rate       201.00%    
Employee Stock Option | Employees | Maximum
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Weighted average exercise price, Granted       $ 1.75    
Discount rate       2.78%    
Expected volatility rate       204.00%    
Non Employee Director Stock Option
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Stock option, term       10 years    
Number of Shares, Granted       88,572    
Weighted average exercise price, Granted       $ 1.75    
Discount rate       1.73%    
Expected life       5 years 3 months    
Expected volatility rate       201.00%    
Fair value stock granted during period       $ 151,867    
Stock options vesting percentage, immediately from date of grant       50.00%    
Stock options vesting percentage, remaining of period       50.00%    
Non Employee Director Stock Option | Minimum
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Vesting period       8 months    
Non Employee Director Stock Option | Maximum
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Vesting period       1 year    
2010 Plan
           
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Stock based compensation, common stock shares authorized       625,000    
Share based compensation, common stock shares issued and outstanding       1,094,854