X0306 4 2013-06-30 0 0001069308 Opexa Therapeutics, Inc. OPXA 0001359850 Seaman Scott B C/O OPEXA THERAPEUTICS, INC. 2635 TECHNOLOGY FOREST BLVD. THE WOODLANDS TX 77381 1 0 0 0 Common Stock 2013-06-30 4 A 0 19345 1.54 A 249526 I See footnote On June 30, 2013, 19,345 shares of Common Stock were issued to Alkek & Williams Ventures Ltd ("Ventures") as payment-in-kind for interest accrued as of June 30, 2013 on a 12% Convertible Secured Promissory Note held by Ventures in the principal amount of $500,000. The shares issued in payment of accrued interest payable on the interest payment date were deemed to have a value equal to the volume weighted average price for the Common Stock for the five trading days ending three trading days prior to the payment date. Held by Ventures. Chaswil, Ltd. ("Chaswil") is the investment manager of Ventures and holds voting power and investment power with respect to the Issuer securities held by Ventures. Mr. Seaman is a registered principal of Chaswil and has shared voting power and/or investment power with respect to the Issuer securities held by Ventures. /s/ John Ginzler by Power of Attorney 2013-07-02